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Invitrogen™ PDE11A Polyclonal Antibody
Rabbit Polyclonal Antibody
Brand: Invitrogen™ PA529076
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Description
Recommended positive controls: PC-3. Predicted reactivity: Mouse (99%), Rat (99%), Bovine (99%). Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
The 3',5'-cyclic nucleotides cAMP and cGMP function as second messengers in a wide variety of signal transduction pathways. 3',5'-cyclic nucleotide phosphodiesterases (PDEs) catalyze the hydrolysis of cAMP and cGMP to the corresponding 5'-monophosphates and provide a mechanism to downregulate cAMP and cGMP signaling. This gene encodes a member of the PDE protein superfamily. Mutations in this gene are a cause of Cushing disease and adrenocortical hyperplasia. Multiple transcript variants encoding different isoforms have been found for this gene.
Specifications
| PDE11A | |
| Polyclonal | |
| Unconjugated | |
| PDE11A | |
| 6330414F14Rik; A630086N24Rik; cAMP and cGMP cyclic nucleotide phosphodiesterase 11A; cAMP and cGMP phosphodiesterase 11A; Dual 3',5'-cyclic-AMP and -GMP phosphodiesterase 11A; FLJ23693; Gm350; MGC133355; MGC133356; Pde11a; PDE11A1; phosphodiesterase 11A; PPNAD2 | |
| Rabbit | |
| Antigen affinity chromatography | |
| RUO | |
| 50940 | |
| Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. | |
| Liquid |
| Immunohistochemistry (Paraffin), Western Blot | |
| 1 mg/mL | |
| PBS with 1% BSA, 20% glycerol and 0.01% thimerosal; pH 7 | |
| Q9HCR9 | |
| PDE11A | |
| Recombinant protein encompassing a sequence within the center region of human PDE11A. The exact sequence is proprietary. | |
| 100 μL | |
| Primary | |
| Human | |
| Antibody | |
| IgG |
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