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Invitrogen™ PDE1C Polyclonal Antibody

Rabbit Polyclonal Antibody
Brand: Invitrogen™ PA532969
Description
Percent identity with other species by BLAST analysis: Human, Gorilla, Orangutan, Gibbon, Monkey, Marmoset, Mouse, Rat, Bovine, Dog, Bat, Hamster, Elephant, Panda, Horse, Rabbit (100%); Opossum (88%). For IHC(P), use heat induced antigen retrieval in pH 6.0 citrate buffer. After incubation with the primary antibody, slides were incubated with biotinylated secondary antibody, followed by alkaline phosphatase-streptavidin and chromogen.
Cyclic nucleotide phosphodiesterases (PDEs) catalyze hydrolysis of the cyclic nucleotides cAMP and cGMP to the corresponding nucleoside 5-prime-monophosphates. Mammalian PDEs have been classified into several families based on their biochemical properties. Members of the PDE1 family, such as PDE1C, are calmodulin -dependent PDEs (CaM-PDEs) that are stimulated by a calcium-calmodulin complex (Repaske et al., 1992 ).
Specifications
| PDE1C | |
| Polyclonal | |
| Unconjugated | |
| PDE1C | |
| 3',5'-cyclic-AMP phosphodiesterase; 3',5'-cyclic-GMP phosphodiesterase; Calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1C; cam-PDE 1C; cyclic nucleotide phosphodiesterase 1 C; Hcam3; hCam-3; Human 3',5' cyclic nucleotide phosphodiesterase (HSPDE1C1A); PDE1C; phosphodiesterase 1C; phosphodiesterase 1C calmodulin-dependent (70kD); phosphodiesterase 1C, calmodulin-dependent 70kDa | |
| Rabbit | |
| Antigen affinity chromatography | |
| RUO | |
| 100070015, 100347155, 100774969, 18575, 475272, 5137, 526211, 81742 | |
| Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. | |
| Liquid |
| Immunohistochemistry (Paraffin) | |
| 0.21 mg/mL | |
| PBS with 0.1% sodium azide | |
| Q14123, Q63421, Q64338 | |
| PDE1C | |
| Synthetic 16 amino acid peptide from C-terminus of human PDE1C. | |
| 50 μg | |
| Primary | |
| Human, Mouse, Rat, Canine, Rabbit, Monkey, Bovine, Hamster, Horse, Bat | |
| Antibody | |
| IgG |
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