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PDE4B Mouse anti-Human, Clone: OTI3B12, lyophilized, TrueMAB™

Product Code. 17673161
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Quantity:
100 μg
Unit Size:
100µg
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17673161 100 μg 100µg
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Product Code. 17673161 Supplier Origene Technologies Supplier No. CF503477

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Description

Mouse Monoclonal Antibody

Reconstitute with PBS (pH 7.3) and recommend to perform another round of desalting process using Product No. 7KMWCO

This gene is a member of the type IV, cyclic AMP (cAMP)-specific, cyclic nucleotide phosphodiesterase (PDE) family. Cyclic nucleotides are important second messengers that regulate and mediate a number of cellular responses to extracellular signals, such as hormones, light, and neurotransmitters. The cyclic nucleotide phosphodiesterases (PDEs) regulate the cellular concentrations of cyclic nucleotides and thereby play a role in signal transduction. This gene encodes a protein that specifically hydrolyzes cAMP. Altered activity of this protein has been associated with schizophrenia and bipolar affective disorder. Alternate transcriptional splice variants, encoding different isoforms, have been characterized.

Specifications

Antigen PDE4B
Applications Flow Cytometry, Immunohistochemistry (Paraffin), Western Blot
Classification Monoclonal
Clone OTI3B12
Conjugate Unconjugated
Formulation PBS with 8% trehalose and no preservative; pH 7.3
Gene PDE4B
Gene Accession No. Q07343
Gene Alias DPDE4, PDEIVB
Gene Symbols PDE4B
Host Species Mouse
Immunogen Full length human recombit protein of human PDE4B produced in HEK293T cell.
Purification Method Affinity Chromatography
Quantity 100 μg
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 5142
Target Species Human
Content And Storage -20° C, Avoid Freeze/Thaw Cycles
Product Type Antibody
Form Lyophilized
Isotype IgG2b
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