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PDGFC Rabbit anti-Human, Mouse, Polyclonal, Proteintech

Product Code. 16836525 Shop All Proteintech Products
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20 μL
150 μL
Unit Size:
150µL
20µL
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16836525 20 μL 20µL
16826525 150 μL 150µL
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Product Code. 16836525 Supplier Proteintech Supplier No. 550761AP20UL

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Description

Rabbit Polyclonal Antibody

Sphingosine Kinase 2 (Sphk2) catalyzes the phosphorylation of sphingosine to sphingosine 1 phosphate (S1P), an important signaling molecule with intra- and extracellular functions. Inside the cell S1P acts as a signaling molecule like other sphingolipid metabolites like ceramide and sphingosine. S1P has been implicated in regulating cell differentiation, calcium mobilization from intracellular stores, and apoptosis. The cell surface receptors for S1P are the EDG family of G protein-coupled receptors (S1P Receptors).These receptors couple to multiple G proteins (e.g. S1P1 couples to Gi whereas S1P2 and S1P3 couple to Gq, G13 in addition to Gi) and regulate a extremely wide range of cellular events including cell motility, survival, apoptosis, migration and cellcell interaction. Important roles for S1P have also been reported in regulation of cardiogenesis, vascular maturation, oocyte survival, immune cell trafficking, cells of the neuronal system and bone cells. S1P levels are regulated by the activity of Sphk (Sphk1 and Sphk2).

Specifications

Antigen PDGFC
Applications Western Blot
Classification Polyclonal
Concentration 0.19 mg/mL
Conjugate Unconjugated
Formulation 0.1 M glycine, 0.1 M sodium bicarbonate with 50% glycerol and 0.02% sodium azide; pH 7.3
Gene PDGFC
Gene Accession No. Q8CI19, Q9NRA1
Gene Alias FALLOTEIN, PDGF C, PDGFC, PDGFC receptor binding form, SCDGF, VEGF E
Gene Symbols Pdgfc
Host Species Rabbit
Immunogen Peptide
Purification Method Antigen Affinity Chromatography
Quantity 20 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 54635, 56034
Target Species Human, Mouse
Content And Storage -20°C
Product Type Antibody
Form Liquid
Isotype IgG
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