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PDGFRB Monoclonal Antibody (OTI3B5), TrueMAB™, OriGene
Mouse Monoclonal Antibody
Brand: Origene Technologies TA506231
This item is not returnable.
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Description
PDGFRb is a cell surface tyrosine kinase receptor for members of the platelet-derived growth factor family. These growth factors are mitogens for cells of mesenchymal origin. The identity of the growth factor bound to a receptor monomer determines whether the functional receptor is a homodimer or a heterodimer, composed of both platelet-derived growth factor receptor alpha and beta polypeptides. The gene is flanked on chromosome 5 by the genes for granulocyte-macrophage colony-stimulating factor and macrophage-colony stimulating factor receptor; all three genes may be implicated in the 5-q syndrome. A translocation between chromosomes 5 and 12, that fuses this gene to that of the translocation, ETV6, leukemia gene, results in chronic myeloproliferative disorder with eosinophilia.Specifications
| PDGFRB | |
| Monoclonal | |
| 1 mg/mL | |
| PBS with 1% BSA, 50% glycerol and 0.02% sodium azide | |
| P09619 | |
| PDGFRB | |
| Full length human recombit protein of human PDGFRB produced in HEK293T cell. | |
| 100 μL | |
| Primary | |
| Human | |
| Antibody | |
| IgG1 |
| Immunocytochemistry, Immunofluorescence, Western Blot | |
| OTI3B5 | |
| Unconjugated | |
| PDGFRB | |
| CD140B, IBGC4, IMF1, JTK12, KOGS, PDGFR, PDGFR-1, PDGFR1, PENTT | |
| Mouse | |
| Affinity Chromatography | |
| RUO | |
| 5159 | |
| -20° C, Avoid Freeze/Thaw Cycles | |
| Liquid |
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