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PDX1 Monoclonal Antibody (OTI3H3), TrueMAB™, OriGene
Mouse Monoclonal Antibody
Brand: Origene Technologies TA807372
This item is not returnable.
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Description
pdx-1 (pancreas duodenum homeobox-1, also known as IPF-1, IDX-1, and STF-1) is a transcription factor that has been shown to activate insulin, glucokinase, IAPP, and somatostatin gene transcription. Significant interest surrounds this proteins glucose-dependent regulation of insulin gene transcription. Additionally, pdx-1 has been studied for its role in pancreatic development which includes maturation and differentiation of pancreatic precursor cells. Mutations in the pdx-1 gene have been shown to cause pancreatic agenesis, maturity-onset diabetes of the young, and type II diabetes.Specifications
| PDX1 | |
| Monoclonal | |
| 1 mg/mL | |
| PBS with 1% BSA, 50% glycerol and 0.02% sodium azide | |
| P52945 | |
| PDX1 | |
| Full length human recombit protein of human PDX1 produced in E.coli. | |
| 100 μL | |
| Primary | |
| Human | |
| Antibody | |
| IgG2a |
| Immunohistochemistry (Paraffin) | |
| OTI3H3 | |
| Unconjugated | |
| PDX1 | |
| GSF, IDX-1, IPF1, IUF1, MODY4, PAGEN1, PDX-1, STF-1 | |
| Mouse | |
| Affinity Chromatography | |
| RUO | |
| 3651 | |
| -20° C, Avoid Freeze/Thaw Cycles | |
| Liquid |
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