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Description
Antibody detects endogenous levels of total PDZD2.
Proteins containing PDZ domains have been shown frequently to bind the C-termini of transmembrane receptors or ion channels. They have also been shown to bind to other PDZ domain proteins and could possibly be involved in intracellular signaling. The protein encoded by this gene contains six PDZ domains and shares sequence similarity with pro-interleukin-16 (pro-IL-16). Like pro-IL-16, the encoded protein localizes to the endoplasmic reticulum and is thought to be cleaved by a caspase to produce a secreted peptide containing two PDZ domains. In addition, this gene is upregulated in primary prostate tumors and may be involved in the early stages of prostate tumorigenesis.
Specifications
Specifications
| Antigen | PDZD2 |
| Applications | Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry |
| Classification | Polyclonal |
| Concentration | 1 mg/mL |
| Conjugate | Unconjugated |
| Formulation | PBS with 50% glycerol and 0.02% sodium azide; pH 7.4 |
| Gene | PDZD2 |
| Gene Accession No. | O15018, Q9QZR8 |
| Gene Alias | 4930537L06Rik; A930022H17Rik; activated in prostate cancer protein; AIPC; Gm82; KIAA0300; mKIAA0300; PAPIN; PDZ domain containing 2; PDZ domain containing 3; PDZ domain-containing protein 2; PDZ domain-containing protein 3; PDZD2; PDZK3; Pin1; Plakophilin-related armadillo repeat protein-interacting PDZ protein; plakophilin-related armadillo repeat protein-interactive PDZ protein; Processed PDZ domain-containing protein 2 |
| Gene Symbols | PDZD2 |
| Show More |
Product Title
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