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  6. Invitrogen™ Pellino 1 Recombinant Rabbit Monoclonal Antibody (K01_1W56)

Invitrogen™ Pellino 1 Recombinant Rabbit Monoclonal Antibody (K01_1W56)
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Product Code. 30825580
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30828818 50 μL
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Product Code. 30825580 Supplier Invitrogen™ Supplier No. MA563832

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Description

Rabbit Recombinant Monoclonal Antibody

Pellino 1 Recombinant Monoclonal Antibody for Western Blot

The Pellino proteins are a highly homologous family of E3 ubiquitin ligases that act as upstream mediators in Toll-like receptor (TLR) pathways that lead to activation of MAP kinases and transcription factors. Pellino 1 is required for interleukin-1-mediated signaling through its interaction with the IRAK4-IRAK-TRAF6 complex, ultimately resulting in the activation of NF-Kappa-B. Like other members of the Pellino family, Pellino 1 is an E3 ubiquitin ligase, able to catalyze the polyubiquitination of IRAK1. It is activated via phosphorylation by either IRAK1 and IRAK4 or the IKK-related kinases IKK-epsilon; and TBK1. In addition to phosphorylation, Pellino 1 activity is also modulated via ubiquitination and sumoylation.
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Specifications

Antigen Pellino 1
Applications Western Blot
Classification Recombinant Monoclonal
Clone K01_1W56
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation 50mM tris glycine with 150mM NaCl, 40% glycerol, 0.05% BSA and 0.01% sodium azide; pH 7.4
Gene PELI1
Gene Accession No. Q96FA3
Gene Alias 2810468L03Rik; A930031K15Rik; AA409794; AI586297; D11Ertd676e; E3 ubiquitin-protein ligase pellino homolog 1; Peli1; pellino 1; pellino E3 ubiquitin protein ligase 1; pellino homolog 1; pellino1; pellino-1; Pellino-related intracellular-signaling molecule; PRISM; protein pellino homolog 1; RING-type E3 ubiquitin transferase pellino homolog 1
Gene Symbols PELI1
Host Species Rabbit
Immunogen Recombinant protein of human Pellino 1.
Purification Method Protein A/G
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 305549, 57162
Target Species Human, Rat
Content And Storage Maintain refrigerated at 2-8°C for up to 1 month. For long term storage store at -20°C
Product Type Antibody
Form Liquid
Isotype IgG
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