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Tocris Bioscience™ Penitrem A
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Product Code. 18712734
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1 mg
Unit Size:
1mg
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18712734 1 mg 1mg
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Product Code. 18712734 Supplier Tocris Bioscience™ Supplier No. 4617/1

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Description

Potent and selective BKCa (KCa1.1) channel blocker

Potent and selective blocker of BKCa (KCa1.1) channels (IC50 values are 6.4 and 64.4 nM for BKCa channels containing α subunits only, and those containing α and β1 respectively). Displays no effect on native delayed rectifier K+ and KATP currents, or cloned KV1.5 channels. Blocks BKCa channels in both inside-out and cell-attached patches. Shown to enhance smooth muscle contraction in vitro and increase total peripheral resistance in vivo.
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Specifications

CAS 12627-35-9
Quantity 1 mg
Molecular Formula C37H44ClNO6
Formula Weight 634.2
Purity >98%
Molecular Weight (g/mol) 634.21
Chemical Name or Material Penitrem A
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