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Periostin Polyclonal Antibody, Invitrogen™
Rabbit Polyclonal Antibody
Brand: Invitrogen PA598301
Additional Details : Weight : 0.01000kg
Description
Periostin (PN), also designated osteoblast-specific factor 2 (OSF-2), is a disulfide linked protein originally isolated as a osteoblast-specific factor. Periostin is a secreted protein that binds heparin and functions as a ligand for alpha(V)beta(3) and alpha(V)beta(5) integrins. In preosteoblasts, Periostin acts as a cell adhesion molecule and plays a role in osteoblast recruitment, spreading and attachment. Periostin is mainly detected in lower gastrointestinal tract, aorta, stomach, placenta, uterus and breast tissues but is up-regulated in epithelial ovarian tumors and overexpressed in breast cancer. Expression of Periostin is increased by bone morphogenetic protein (BMP2) and transforming growth factor beta 1(TGF beta 1). Periostin contains a typical signal sequence, followed by a cysteine-rich domain, a fourfold repeated domain, which shows homology with the insect protein fasciclin, and a C-terminal domain.Specifications
Periostin | |
Polyclonal | |
Unconjugated | |
POSTN | |
POSTN | |
Recombit Human Periostin protein (24-836AA) | |
100 μg | |
Primary | |
Human, Mouse | |
Antibody | |
IgG |
ELISA, Immunocytochemistry, Immunofluorescence, Immunohistochemistry, Immunohistochemistry (Paraffin) | |
4 mg/mL | |
PBS with 50% glycerol and 0.03% Proclin 300; pH 7.4 | |
Q15063, Q62009 | |
Rabbit | |
Protein G | |
RUO | |
10631, 50706 | |
-20° C, Avoid Freeze/Thaw Cycles | |
Liquid |