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Invitrogen™ PERP Polyclonal Antibody
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Rabbit Polyclonal Antibody

Brand:  Invitrogen™ PA5110879

Product Code. 17138803

  • € 630.00 / 100µL

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Description

Description

Immunogen sequence: LQSSDHGQTS SLWWKCSQEG GGSGSYEEGC QSLMEYAW Highest antigen sequence indentity to the following orthologs: Rat - 82%, Mouse - 82%.

The p53 tumor-suppressor gene integrates numerous signals that control cell life and death. Several novel molecules involved in p53 network, including Chk2, p53R2, p53AIP1, Noxa, PIDD, PID/MTA2, MTBP and PERP, were identified and their genes were cloned recently. PERP, also termed PIGPC1 and THW, is a plasma membrane protein. p53 binds to the promoter of PERP and transcriptionally activates PERP gene then the translated PERP protein mediates the p53 induced apoptosis. The expression of PERP causes cell death. PERP is a mediator of p53 induced apoptosis. PERP has sequence similarity to PMP-22/gas3 and is a new member of the PMP-22/gas3 family.
TRUSTED_SUSTAINABILITY
Specifications

Specifications

PERP
Polyclonal
Unconjugated
PERP
1110017A08Rik; dJ496H19.1; HGNC:17637; KCP1; KCP-1; keratinocyte associated protein 1; keratinocyte-associated protein 1; keratinocytes associated protein 1; KRTCAP1; p53 apoptosis effector related to PMP22; p53 apoptosis effector related to PMP-22; p53 apoptosis-associated target; p53-induced protein PIGPC1; PERP; PERP, TP53 apoptosis effector; PIGPC1; RP3-496H19.1; THW; Transmembrane protein THW
Rabbit
Antigen affinity chromatography
RUO
64065
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Liquid
Immunohistochemistry (Paraffin)
0.10 mg/mL
PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
Q96FX8
PERP
Recombinant Protein corresonding to Human PERP. Recombinant protein control fragment (Product #RP-88749).
100 μL
Primary
Human
Antibody
IgG
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