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PF-8380, MedChemExpress

Product Code. 16436176
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Product Code. 16436176

Brand: Medchem Express HY13344

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Description

MedChemExpress PF-8380 is a potent autotaxin inhibitor with an IC50 of 2.8 nM in isolated enzyme assay and 101 nM in human whole blood.

PF-8380 is a potent autotaxin inhibitor with an IC50 of 2.8 nM in isolated enzyme assay and 101 nM in human whole blood.

Specifications

Chemical Name or Material PF-8380
CAS 1144035-53-9
Color White
Purity Grade Notes Research
Molecular Formula C22H21Cl2N3O5
Quantity 100 mg
Solubility Information DMSO : 6.67 mg/mL (13.94 mM; ultrasonic and adjust pH to 5 with HCl)
SMILES O=C(N1CCN(CC1)CCC(C2=CC(O3)=C(C=C2)NC3=O)=O)OCC4=CC(Cl)=CC(Cl)=C4
Molecular Weight (g/mol) 478.33
Formula Weight 478.33
Percent Purity 95.0%
Grade Research
Physical Form Solid
For Use With (Application) Cancer-Kinase/protease
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Research purposes only

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