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PFK-158, MedChemExpress

Product Code. 16485766
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Product Code. 16485766 Supplier Medchem Express Supplier No. HY12203

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Description

MedChemExpress PFK-158 is a potent and selective PFKFB3 inhibitor with an IC50 value 137 nM. PFK-158 reduces glucose uptake, ATP production, lactate release, and induces apoptosis and autophagy in cancer cells. PFK-158 has broad anti-tumor activity. PFK-158 can also enhance Colistin's resistance to bacteria.

PFK-158 is a potent and selective PFKFB3 inhibitor with an IC50 value 137 nM. PFK-158 reduces glucose uptake, ATP production, lactate release, and induces apoptosis and autophagy in cancer cells. PFK-158 has broad anti-tumor activity. PFK-158 can also enhance Colistin's resistance to bacteria.

Specifications

Chemical Name or Material PFK-158
Physical Form Solid
CAS 1462249-75-7
Color Light Yellow
Quantity 100 mg
Purity Grade Notes Research
Molecular Formula C18H11F3N2O
For Use With (Application) Cancer-programmed cell death
Solubility Information DMSO : ≥ 30 mg/mL (91.38 mM)
SMILES O=C(C1=CC=NC=C1)/C=C/C2=NC3=CC(C(F)(F)F)=CC=C3C=C2
Molecular Weight (g/mol) 328.29
Formula Weight 328.29
Percent Purity 98.52%
Grade Research
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Research purposes only

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