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Invitrogen™ PGA5 Monoclonal Antibody (2C1)
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Product Code. 11345523
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Quantity:
100 μL
Unit Size:
100µL
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Product Code. Quantity unitSize
11345523 100 μL 100µL
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Product Code. 11345523 Supplier Invitrogen™ Supplier No. MA515558

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Description

Mouse Monoclonal Antibody

MA5-15558 targets PGA5 in indirect ELISA, IHC and WB applications and shows reactivity with Human samples. The MA5-15558 immunogen is purified recombinant fragment of human PGA5 expressed in E. Coli. MA5-15558 detects PGA5 which has a predicted molecular weight of approximately 42kDa.

PGA5: Pepsinogen 5, group I (pepsinogen A). Pepsinogens are the inactive precursors of pepsin, the major acid protease found in the stomach. Pepsin is one of the main proteolytic enzymes secreted by the gastric mucosa. Pepsin consists of a single polypeptide chain and arises from its precursor, pepsinogen, by removal of a 41 amino acid segment from the N-terminus. Pepsinogen is synthesized in the stomach lining, and hydrochloric acid, also produced by the gastric mucosa, is necessary to convert the inactive enzyme and to maintain the optimum acidity (pH 1-3) for pepsin function. Pepsin is particularly effective in cleaving peptide bonds involving aromatic amino acids. Pepsin shows extremely broad specificity; although bonds involving phenylalanine and leucine are preferred, many others are also cleaved to some extent. PGA5 is a member of the subfamily A1 within the pepsin family and is the predominant endopeptidase in the gastric juice of vertebrates. PGA5 is inhibited by ovUS-1, a uterine serpin.
TRUSTED_SUSTAINABILITY

Specifications

Antigen PGA5
Applications ELISA, Immunohistochemistry (Paraffin), Western Blot
Classification Monoclonal
Clone 2C1
Concentration Conc. Not Determined
Conjugate Unconjugated
Formulation Ascites with 0.03% sodium azide
Gene Pga5
Gene Accession No. P0DJD9
Gene Alias 1110035E17Rik; Pepf; pepsin A; pepsin A-5; Pepsin F; Pepsinogen 5; pepsinogen 5, group I; pepsinogen 5, group I (pepsinogen A); pepsinogen A; pepsinogen A precursor; pepsinogen A5; pepsinogen F; pepsinogen F protein; pepsinogen precursor; pepsinogen-5; Pg5; PGA; PGA3; PGA4; PGA5
Gene Symbols Pga5
Host Species Mouse
Immunogen Purified recombinant fragment of human PGA5 expressed in E. Coli.
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 5222
Target Species Human
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG1
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