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Invitrogen™ PHF17 Monoclonal Antibody (658005)

Mouse Monoclonal Antibody
Brand: Invitrogen™ MA561645
This item is not returnable.
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Description
Reconstitute with sterile PBS to a final concentration of 0.5 mg/mL.
Scaffold subunit of some HBO1 complexes, which have a histone H4 acetyltransferase activity (PubMed:16387653, PubMed:19187766, PubMed:20129055, PubMed:24065767). Plays a key role in HBO1 complex by directing KAT7/HBO1 specificity towards histone H4 acetylation (H4K5ac, H4K8ac and H4K12ac), regulating DNA replication initiation, regulating DNA replication initiation (PubMed:20129055, PubMed:24065767). May also promote acetylation of nucleosomal histone H4 by KAT5 (PubMed:15502158). Promotes apoptosis (PubMed:16046545). May act as a renal tumor suppressor (PubMed:16046545). Negatively regulates canonical Wnt signaling; at least in part, cooperates with NPHP4 in this function (PubMed:22654112). [UniProt].
Specifications
| PHF17 | |
| Monoclonal | |
| 0.5 mg/mL | |
| PBS with trehalose and no preservative | |
| Q6IE81 | |
| JADE1 | |
| E. coli-derived recombinant human JADE-1/PHF-17, Met1-Ser137. | |
| 100 μg | |
| Primary | |
| Human | |
| Antibody | |
| IgG2b |
| Western Blot, Immunocytochemistry | |
| 658005 | |
| Unconjugated | |
| JADE1 | |
| AU041499; D530048A03Rik; gene for apoptosis and differentiation in epithelia; jade family PHD finger 1; jade family PHD finger protein 1; Jade1; Jade1 PHD finger protein; KIAA1807; mKIAA1807; PHD finger protein 17; PHD protein Jade-1; Phf17; Protein Jade-1 | |
| Mouse | |
| Protein A/G | |
| RUO | |
| 79960 | |
| Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. | |
| Lyophilized |
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