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Invitrogen™ PHF17 Monoclonal Antibody (658005)
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Mouse Monoclonal Antibody

Brand:  Invitrogen™ MA561645

Product Code. 30534765

  • € 469.00 / 100µg

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This item is not returnable. View return policy

Description

Description

Reconstitute with sterile PBS to a final concentration of 0.5 mg/mL.

Scaffold subunit of some HBO1 complexes, which have a histone H4 acetyltransferase activity (PubMed:16387653, PubMed:19187766, PubMed:20129055, PubMed:24065767). Plays a key role in HBO1 complex by directing KAT7/HBO1 specificity towards histone H4 acetylation (H4K5ac, H4K8ac and H4K12ac), regulating DNA replication initiation, regulating DNA replication initiation (PubMed:20129055, PubMed:24065767). May also promote acetylation of nucleosomal histone H4 by KAT5 (PubMed:15502158). Promotes apoptosis (PubMed:16046545). May act as a renal tumor suppressor (PubMed:16046545). Negatively regulates canonical Wnt signaling; at least in part, cooperates with NPHP4 in this function (PubMed:22654112). [UniProt].
TRUSTED_SUSTAINABILITY
Specifications

Specifications

PHF17
Monoclonal
0.5 mg/mL
PBS with trehalose and no preservative
Q6IE81
JADE1
E. coli-derived recombinant human JADE-1/PHF-17, Met1-Ser137.
100 μg
Primary
Human
Antibody
IgG2b
Western Blot, Immunocytochemistry
658005
Unconjugated
JADE1
AU041499; D530048A03Rik; gene for apoptosis and differentiation in epithelia; jade family PHD finger 1; jade family PHD finger protein 1; Jade1; Jade1 PHD finger protein; KIAA1807; mKIAA1807; PHD finger protein 17; PHD protein Jade-1; Phf17; Protein Jade-1
Mouse
Protein A/G
RUO
79960
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Lyophilized
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