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Invitrogen™ PHGDH Polyclonal Antibody
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Product Code. 13461707
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Quantity:
100 μL
Unit Size:
100µL
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13461707 100 μL 100µL
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Product Code. 13461707 Supplier Invitrogen™ Supplier No. PA527579

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Description

Rabbit Polyclonal Antibody

Recommended positive controls: 293T, A431, Jurkat, Raji, HeLa. Predicted reactivity: Mouse (96%), Rat (97%), Pig (90%), Chimpanzee (100%), Bovine (83%). Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.

PHGDH gene encodes the enzyme which is involved in the early steps of L-serine synthesis in animal cells. L-serine is required for D-serine and other amino acid synthesis. The enzyme requires NAD/NADH as a cofactor and forms homotetramers for activity. Mutations in this gene have been found in a family with congenital microcephaly, psychomotor retardation and other symptoms. Multiple alternatively spliced transcript variants have been found, however the full-length nature of most are not known.
TRUSTED_SUSTAINABILITY

Specifications

Antigen PHGDH
Applications Immunohistochemistry (Frozen), Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry
Classification Polyclonal
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with 1% BSA, 20% glycerol and 0.01% thimerosal; pH 7
Gene PHGDH
Gene Accession No. O08651, O43175, Q61753
Gene Alias 2-oxoglutarate reductase; 3PGDH; 3-PGDH; 3-phosphoglycerate dehydrogenase; 3-phosphoglycerate dehyrogenase; 4930479N23; A10; D-3-phosphoglycerate dehydrogenase; epididymis secretory protein Li 113; HEL-S-113; Malate dehydrogenase; NLS; NLS1; PDG; PGAD; PGD; PGDH; PGDH3; Phgdh; PHGDHD; phosphoglycerate dehydrogenase; SERA
Gene Symbols PHGDH
Host Species Rabbit
Immunogen Recombinant protein encompassing a sequence within the center region of human PHGDH. The exact sequence is proprietary.
Purification Method Antigen affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 236539, 26227, 58835
Target Species Human, Mouse, Rat
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
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