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Invitrogen™ pho Polyclonal Antibody
Rabbit Polyclonal Antibody
Brand: Invitrogen™ PA5144384
This item is not returnable.
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Description
pho Polyclonal Antibody for Western Blot, ELISA
Polycomb group (PcG) protein that binds to the 5'-CNGCCATNNNNG-3' sequence found in the regulatory regions of many genes. PcG proteins act by forming multiprotein complexes, which are required to maintain the transcriptionally repressive state of homeotic genes throughout development. PcG proteins are not required to initiate repression, but to maintain it during later stages of development. They probably act via the methylation of histones, rendering chromatin heritably changed in its expressibility. Probably targets the Esc/E(z) complex to DNA. Necessary but not sufficient to recruit a functional PcG repressive complex that represses target genes, suggesting that the recruitment of the distinct PRC1 complex is also required to allow a subsequent repression.
Specifications
| pho | |
| Polyclonal | |
| Unconjugated | |
| pho | |
| Polycomb protein PHO pho CG17743 | |
| Rabbit | |
| Protein G | |
| RUO | |
| 43819 | |
| -20°C or -80°C if preferred | |
| Liquid |
| ELISA, Western Blot | |
| 3.05 mg/mL | |
| PBS with 50% glycerol and 0.03% Proclin 300; pH 7.4 | |
| Q8ST83 | |
| pho | |
| Recombinant Drosophila melanogaster (Fruit fly) pho protein (1-250aa ). | |
| 100 μL | |
| Primary | |
| Drosophila | |
| Antibody | |
| IgG |
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