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  6. Invitrogen™ Phospho-4EBP1 (Thr37, Thr46) Recombinant Rabbit Monoclonal Antibody (4EB1T37T46-A5), FITC, Invitrogen™

Invitrogen™ Phospho-4EBP1 (Thr37, Thr46) Recombinant Rabbit Monoclonal Antibody (4EB1T37T46-A5), FITC, Invitrogen™

Product Code. 17196828 Shop All Thermo Scientific Products
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Product Code. 17196828 Supplier Invitrogen™ Supplier No. MA537243

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Description

Rabbit Recombinant Monoclonal Antibody

This gene encodes one member of a family of translation repressor proteins. The protein directly interacts with eukaryotic translation initiation factor 4E, which is a limiting component of the multisubunit complex that recruits 40S ribosomal subunits to the 5' end of mRNAs. Interaction of this protein with eIF4E inhibits complex assembly and represses translation. This protein is phosphorylated in response to various signals including UV irradiation and insulin signaling, resulting in its dissociation from eIF4E and activation of mRNA translation.
TRUSTED_SUSTAINABILITY

Specifications

Antigen Phospho-4EBP1 (Thr37, Thr46)
Applications Flow Cytometry
Classification Recombinant Monoclonal
Clone 4EB1T37T46-A5
Conjugate FITC
Formulation PBS with 0.20% BSA and 0.09% sodium azide
Gene EIF4EBP1
Gene Accession No. Q13541, Q60876, Q62622
Gene Alias 4EBP1; 4E-BP1; AA959816; BP-1; eIF4E-binding protein 1; EIF4EBP1; eukaryotic translation initiation factor 4E binding protein 1; eukaryotic translation initiation factor 4E-binding protein 1; MGC431; MGC4316; P/OKCL.6; PHAS-1; PHAS-I; Phosphorylated heat- and acid-stable protein regulated by insulin 1
Gene Symbols EIF4EBP1
Host Species Rabbit
Immunogen A synthetic phospho-peptide corresponding to residues surrounding Thr37/46 of human phospho 4E-BP1.
Purification Method Protein A/G
Quantity 10 Tests
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 116636, 13685, 1978
Target Species Human, Mouse, Rat
Content And Storage 4°C, store in dark
Product Type Antibody
Form Liquid
Isotype IgG κ
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