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Invitrogen™ Phospho-53BP1 (Ser25, Ser29) Polyclonal Antibody
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Product Code. 17207313 Shop All Thermo Scientific Products
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100 μL
Unit Size:
100µL
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17207313 100 μL 100µL
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Product Code. 17207313 Supplier Invitrogen™ Supplier No. PA5114545

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Description

Rabbit Polyclonal Antibody

Antibody detects endogenous levels of 53BP1 only when phosphorylated at Ser25/29.

53BP1 (P53-binding protein 1) plays a critical role in tumor suppression and is a putative substrate of ATM kinase. Upon DNA damage, 53BP1 is phosphorylated and localizes to the presumptive sites of damage, specifically, double-strand breaks. 53BP1 may have a role in checkpoint signaling during mitosis, enhances TP53-mediated transcriptional activation, and participates in DNA repair by maintaining genomic stability.
TRUSTED_SUSTAINABILITY

Specifications

Antigen Phospho-53BP1 (Ser25, Ser29)
Applications Immunohistochemistry (Paraffin), Western Blot
Classification Polyclonal
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.02% sodium azide
Gene TP53BP1
Gene Accession No. P70399, Q12888
Gene Alias 53BP1; FLJ41424; m53BP1; MGC138366; murine p53-binding protein; p202; p53-binding protein 1; p53BP1; TDRD30; TP53; TP53-binding protein 1; Tp53bp1; transformation related protein 53 binding protein 1; transformation related protein 53 binding-protein 1; Trp53bp1; tumor protein 53-binding protein, 1; tumor protein p53 binding protein 1; tumor protein p53-binding protein, 1; tumor suppressor p53-binding protein 1
Gene Symbols TP53BP1, Trp53bp1
Host Species Rabbit
Immunogen A synthesized peptide derived from human 53BP1 around the phosphorylation site of Ser25/29.
Purification Method sequential chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 27223, 296099, 7158
Target Species Human, Mouse, Rat, Monkey
Content And Storage -20°C
Product Type Antibody
Form Liquid
Isotype IgG
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