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Phospho-53BP1 (Ser6) Polyclonal Antibody, Invitrogen™

Product Code. 15565321
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Quantity:
100 μg
Unit Size:
100µg
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15565321 100 μg 100µg
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Product Code. 15565321 Supplier Invitrogen Supplier No. PA538399

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Description

Rabbit Polyclonal Antibody

53BP1 (P53-binding protein 1) plays a critical role in tumor suppression and is a putative substrate of ATM kinase. Upon DNA damage, 53BP1 is phosphorylated and localizes to the presumptive sites of damage, specifically, double-strand breaks. 53BP1 may have a role in checkpoint signaling during mitosis, enhances TP53-mediated transcriptional activation, and participates in DNA repair by maintaining genomic stability.
TRUSTED_SUSTAINABILITY

Specifications

Antigen Phospho-53BP1 (Ser6)
Applications Immunohistochemistry (Paraffin), Western Blot
Classification Polyclonal
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation Dulbecco′s PBS with 150mM NaCl, 50% glycerol and 0.02% sodium azide; pH 7.4
Gene TP53BP1
Gene Accession No. Q12888, P70399
Gene Alias p202, p53-binding protein 1, tumor protein 53-binding protein, tumor suppressor p53-binding protein 1
Gene Symbols TP53BP1, Trp53bp1
Host Species Rabbit
Immunogen A synthetic phosphopeptide derived from human 53BP1 around the phosphorylation site of Ser6 (T-G-SP-Q-L)
Purification Method Antigen affinity chromatography
Quantity 100 μg
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 27223, 296099, 7158
Target Species Human, Mouse, Non-human Primate, Rat
Content And Storage -20°C
Product Type Antibody
Form Liquid
Isotype IgG
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