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Invitrogen™ Phospho-Actin (Tyr53) Polyclonal Antibody
Rabbit Polyclonal Antibody
Brand: Invitrogen™ PA5143643
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Description
This antibody detects a 42 kDa* protein corresponding to the molecular mass of Actin on SDS-PAGE immunoblots of pervanadate treated human C2C12 and SYF cSrc transformed cells, but not in control cells. In addition, this antibody either detects actin cleavage products at 36 and 20 kDa, or cross-reacts with unidentified proteins at these molecular weights in C2C12 cells.
Actin exists as a ubiquitous protein involved with filament formation that make up large portions of the cytoskeleton. Actin filaments interact with myosin to assist in muscle contraction as well as aiding in cell motility and cytokinesis. In vertebrates there are three groups of actin isoforms: alpha, beta and gamma. The alpha actins are found in muscle tissues and are a major constituent of the contractile apparatus. The beta and gamma actins co-exists in most cell types as components of the cytoskeleton and as mediators of internal cell motility.
Specifications
| Phospho-Actin (Tyr53) | |
| Polyclonal | |
| Unconjugated | |
| Acta1 | |
| 0610041G09Rik; 5C actin; A; A4V404_DROME; AA959943; a-actin; AAT6; Ac5C; act; act 5C; ACT1_DROME; Act4; ACT-4; Act5; ACT-5; Act5c; Act-5C; Act5C-PA; Act5C-PB; Act5C-PC; Act5C-PD; Act5C-PE; acta; ACTA1; ACTA1 protein; acta1.S; acta2; Acta-2; ACTA3; ACTB; actb.L; ACTC; ACTC1; Actc-1; ACTE; Actg; ACTG1; Actg2; ACTGE; Actin; actin 5 C; actin 5c; actin A1; actin alpha 1; actin alpha 1, skeletal muscle; actin alpha 2, smooth muscle; actin alpha cardiac; actin alpha cardiac 1; actin alpha cardiac muscle 1; actin beta; actin gamma 1; actin gamma 2, smooth muscle; actin homolog; actin, alpha 1, skeletal muscle; actin, alpha 1, skeletal muscle S homeolog; actin, alpha 2, smooth muscle, aorta; actin, alpha cardiac muscle 1; Actin, alpha cardiac muscle 1, intermediate form; Actin, alpha skeletal muscle; actin, alpha skeletal muscle S homeolog; Actin, alpha skeletal muscle, intermediate form; actin, alpha, cardiac 1; actin, alpha, cardiac muscle; actin, alpha, cardiac muscle 1; actin, alpha, vascular smooth muscle; Actin, aortic smooth muscle; Actin, aortic smooth muscle, intermediate form; actin, beta; actin, beta L homeolog; actin, beta, cytoplasmic; actin, cytoplasmic 1; Actin, cytoplasmic 1, N-terminally processed; Actin, cytoplasmic 2; Actin, cytoplasmic 2, N-terminally processed; Actin, cytoplasmic type 5; actin, cytoplasmic, type 5; actin, gamma 1; actin, gamma 1 propeptide; actin, gamma 2; actin, gamma 2, smooth muscle, enteric; actin, gamma, cytoplasmic 1; actin, gamma-enteric smooth muscle; Actin, gamma-enteric smooth muscle, intermediate form; Actin/BAP47; Actin5C; Actin-5C; actin-like protein; Actl; ACTL3; Acts; ACTSA; ACTSG; Actsk-1; Actvs; Actx; AL023024; alpha 1 skeletal muscle actin; alpha actin; alpha actin 1; alpha actin 2; alpha-actin; alpha-actin cardiac; alpha-actin-1; Alpha-actin-2; alpha-actin-3; alphac-actin; Alpha-cardiac actin; alphaSMA; alpha-sma; alpha-smooth muscle actin; anon-EST:fe2D2; anon-fast-evolving-2D2; ArpA; ASD5; asma; a-SMA; Atcb; Bact; Bact; actin; B-actin; Bap47; beta actin; beta cytoskeletal actin; beta-actin; beta-actin FE-3; beta-actin/Bap47; BRWS1; BRWS2; cardiac actin; cardiac muscle alpha actin 1; cell growth-inhibiting gene 46 protein; cellular cytoskeletal beta-actin; CFTD; CFTD1; CFTDM; CG4027; CG4027-PA; CG4027-PB; CG4027-PC; CG4027-PD; CG4027-PE; chrX:5748184..5748304; CMD1R; CMH11; cyt5C; cytoplasmic 1; cytoplasmic 2; cytoplasmic actin; cytoplasmic beta-actin; cytoplasmic type 5; cytoskeletal beta actin; cytoskeletal gamma-actin; cytoskeletal protein; deafness, autosomal dominant 20; deafness, autosomal dominant 26; DFNA20; DFNA26; Dm-actin5C; Dmel\CG4027; Dmel_CG4027; E430023M04Rik; E51; epididymis luminal protein 176; F-actin; G-actin; gamma 1 propeptide; gamma non-muscle actin; gamma-2-actin; Gamma-actin; gamma-enteric smooth muscle actin; GIG46; HEL-176; hypothetical protein LOC515610; I79_002310; I79_013242; I79_019066; l(1)G0009; l(1)G0010; l(1)G0025; l(1)G0079; l(1)G0117; l(1)G0177; l(1)G0245; l(1)G0330; l(1)G0420; l(1)G0486; LOW QUALITY PROTEIN: actin, alpha skeletal muscle; LOW QUALITY PROTEIN: actin, aortic smooth muscle; LVNC4; M32055; mpfd; MYMY5; NEM1; NEM2; NEM3; nemaline myopathy type 3; pan actin; PS1TP5-binding protein 1; PS1TP5BP1; RE02927p; RP5-1068B5.2; SHPM; similar to b-actin; similar to beta actin; skeletal alpha actin; sma; SMalphaA; SMGA; smooth muscle alpha-actin; smooth muscle gamma-actin; T11; type 5; unnamed protein product; vascular smooth muscle alpha-actin; VSCM; wu:fb63d03; XELAEV_18029136mg; XELAEV_18045052mg | |
| Rabbit | |
| Antigen affinity chromatography | |
| RUO | |
| 11459, 11461, 11464, 11465, 11468, 11475, 25365, 287876, 29275, 29437, 58, 59, 60, 70, 71, 72, 81633, 81822 | |
| -20°C, Avoid Freeze/Thaw Cycles | |
| Liquid |
| Western Blot, Immunocytochemistry | |
| 0.25 mg/mL | |
| PBS with 1mg/mL BSA, 50% glycerol and 0.05% sodium azide | |
| P60709, P60710, P60711, P62736, P62737, P62738, P63259, P63260, P63261, P63267, P63268, P63269, P68032, P68033, P68035, P68133, P68134, P68136 | |
| Acta1, ACTA2, ACTB, ACTC1, ACTG1, ACTG2 | |
| Phospho-Actin (Tyr-53) synthetic peptide (coupled to KLH) corresponding to amino acid residues around tyrosine 53 of human beta actin. This sequence is identical to similar regions in all four alpha actins, as well as in gamma actin, and is well conserved in actins from most eukaryotic species. | |
| 100 μL | |
| Primary | |
| Human, Mouse, Rat | |
| Antibody | |
| IgG |
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