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Invitrogen™ Phospho-ALOX5 (Ser663) Polyclonal Antibody

Description
Phospho-ALOX5 (Ser663) Polyclonal Antibody detects endogenous levels of ALOX5 only when phosphorylated at Ser663.
This gene encodes a protein which, with Arachidonate 5-lipoxygenase-activating protein, is required for leukotriene synthesis. Leukotrienes are arachidonic acid metabolites which have been implicated in various types of inflammatory responses, including asthma, arthritis and psoriasis. This protein localizes to the plasma membrane. Inhibitors of its function impede translocation of 5-lipoxygenase from the cytoplasm to the cell membrane and inhibit 5-lipoxygenase activation.
Specifications
Specifications
| Antigen | Phospho-ALOX5 (Ser663) |
| Applications | Western Blot |
| Classification | Polyclonal |
| Concentration | 1 mg/mL |
| Conjugate | Unconjugated |
| Formulation | PBS with 50% glycerol and 0.02% sodium azide; pH 7.4 |
| Gene | ALOX5 |
| Gene Accession No. | P09917, P12527, P48999 |
| Gene Alias | 5 - Lipoxygenase; 5-lipoxygenase; 5LO; 5-LO; 5-LOX; 5LPG; 5LX; AI850497; ALOX5; Arachidonate 5-lipoxygenase; arachidonic 5-lipoxygenase alpha-10 isoform; arachidonic 5-lipoxygenase delta-10-13 isoform; arachidonic 5-lipoxygenase delta-13 isoform; arachidonic 5-lipoxygenase delta-p10 isoform; arachidonic acid 5-lipoxygenase; F730011J02; leukotriene A4 synthase; LOG5; LOW QUALITY PROTEIN: arachidonate 5-lipoxygenase; lox5; LOX-5; LOX5A; polyunsaturated fatty acid 5-lipoxygenase; RP11-67C2.3 |
| Gene Symbols | ALOX5 |
| Show More |
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