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Invitrogen™ Phospho-ANKRD28 (Ser1007) Polyclonal Antibody
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Rabbit Polyclonal Antibody

Brand:  Invitrogen™ PA5105964

Product Code. 16652405

  • € 493.00 / 100µL

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Description

Description

Antibody detects endogenous levels of ANKRD28 only when phosphorylated at Ser1007.

Putative regulatory subunit of protein phosphatase 6 (PP6) that may be involved in the recognition of phosphoprotein substrates. Involved in the PP6-mediated dephosphorylation of NFKBIE opposing its degradation in response to TNF-alpha. Selectively inhibits the phosphatase activity of PPP1C. Targets PPP1C to modulate HNRPK phosphorylation. ANKRD28 selectively regulated phosphorylation of hnRNP-K at ser284, an effect that was enhanced in vivo by an S1013A/S1017A double mutant, suggesting that ANKRD28 targets PP1 in a regulated manner to dephosphorylate hnRNP-K selectively at ser284.
TRUSTED_SUSTAINABILITY
Specifications

Specifications

Phospho-ANKRD28 (Ser1007)
Polyclonal
Unconjugated
ANKRD28
AI465466; AI604979; ANKRD28; ankyrin repeat domain 28; ankyrin repeat domain-containing protein 28; E430019N21Rik; KIAA0379; mKIAA0379; phosphatase interactor targeting K protein; phosphatase interactor targeting protein hnRNP K; PITK; PP6-ARS-A; PPP1R65; protein phosphatase 1, regulatory subunit 65; protein phosphatase 6 ankyrin repeat subunit A; RGD1559931; serine/threonine-protein phosphatase 6 regulatory ankyrin repeat subunit A; serine/threonine-protein phosphatase 6 regulatory subunit ARS-A
Rabbit
Sequential Chromatography
RUO
105522, 23243
-20°C
Liquid
Immunohistochemistry (Paraffin), Western Blot
1 mg/mL
PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
O15084, Q505D1
ANKRD28
A synthesized peptide derived from human ANKRD28(Accession O15084), corresponding to amino acid residues around phosphorylated Ser1007.
100 μL
Primary
Human, Mouse
Antibody
IgG
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