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Invitrogen™ Phospho-Arp2 (Thr237, Thr238) Polyclonal Antibody

Rabbit Polyclonal Antibody
Brand: Invitrogen™ PA5143650
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Description
The antibody detects 44 and 32 kDa* proteins corresponding to the molecular mass of Arp2 on SDS-PAGE immunoblots of human A431 and Jurkat cells treated with Calyculin A. This reactivity is not observed after lambda phosphatase treatment.
ARP2 (actin-related protein 2) is an ATP-binding component of the ARP2/3 complex - a multiprotein complex that mediates actin polymerization upon stimulation by the nucleation-promoting factor (NPF). The ARP2/3 complex mediates the formation of branched actin networks in the cytoplasm and provides the force for cell motility. The ARP2/3 complex also promotes actin polymerization in the nucleus, thereby regulating gene transcription and repair of damaged DNA.
Specifications
| Phospho-Arp2 (Thr237, Thr238) | |
| Polyclonal | |
| Unconjugated | |
| ACTR2 | |
| 4921510D23Rik; AA409782; Actin-like protein 14D; Actin-like protein 2; Actin-related protein 14 Da; Actin-related protein 14D; Actin-related protein 2; Actr14D; Actr2; Arp14D; ARP2; ARP2 actin related protein 2 homolog; ARP2 actin-related protein 2; ARP2 actin-related protein 2 homolog; ARP2 actin-related protein 2 homolog (yeast); Arp2-PA; Arp2-PB; Arp2-PC; CG9901; CG9901-PA; CG9901-PB; CG9901-PC; D6Ertd746e; Dmel\CG9901; Dmel_CG9901; I79_003843; LD18955p | |
| Rabbit | |
| Antigen affinity chromatography | |
| RUO | |
| 10097, 289820, 66713 | |
| -20°C, Avoid Freeze/Thaw Cycles | |
| Liquid |
| Western Blot, Immunocytochemistry | |
| ~1 mg/mL | |
| PBS with 1mg/mL BSA, 50% glycerol and 0.05% sodium azide | |
| P61160, P61161, Q5M7U6 | |
| ACTR2 | |
| Phospho-Arp2 (Thr-237/Thr-238) synthetic peptide (coupled to KLH) corresponding to amino acid residues surrounding threonine 237 and threonine 238 in human Arp2. This peptide sequence is highly conserved in rat, mouse, chicken, and fish Arp2 proteins. | |
| 100 μL | |
| Primary | |
| Human, Mouse, Rat | |
| Antibody | |
| IgG |
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