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Invitrogen™ Phospho-Aurora B/C (Thr236, Thr202) Polyclonal Antibody
Rabbit Polyclonal Antibody
Brand: Invitrogen™ PA536030
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Description
This antibody detects endogenous protein at a molecular weight of 35 and 39 kDa. Purity is >95% by SDS-PAGE.
Aurora kinases belong to a highly conserved family of mitotic serine/threonine kinases with three members identified among mammals: Aurora A, B, and C. Studies on the temporal expression pattern and subcellular localization of Aurora kinases in mitotic cells suggest an association with mitotic structure. Aurora kinase functional influences span from G2 phase to cytokinesis and may be involved in key cell cycle events such as centrosome duplication, chromosome bi-orientation and segregation, cleavage furrow positioning, and ingression.
Specifications
| Phospho-Aurora B/C (Thr236, Thr202) | |
| Polyclonal | |
| Unconjugated | |
| AURKC | |
| AIE1; AIE2; Aik2; AIK3; Aim1; AIM-1; AIRK2; AIRK3; AL022959; ARK2; ARK-2; ARK3; ARK-3; AurB; AurC; Aurkb; aurkb-sv1; aurkb-sv2; Aurkc; Aurora 1; aurora 3; Aurora- and IPL1-like midbody-associated protein 1; aurora B; aurora kinase B; aurora kinase B-Sv1; aurora kinase B-Sv2; aurora kinase C; aurora/Ipl1/Eg2 protein 1; aurora/IPL1/EG2 protein 2; aurora/IPL1-related kinase 2; Aurora/IPL1-related kinase 3; aurora-1; aurora-B; aurora-C; aurora-related kinase 2; aurora-related kinase 3; epididymis secretory protein Li 90; HEL-S-90; IAK3; IPL1; PPP1R48; protein phosphatase 1, regulatory subunit 48; serine/threonine kinase 12; serine/threonine kinase 13 (aurora/IPL1-like); serine/threonine kinase 13 (aurora/IPL-like); serine/threonine kinase 5; serine/threonine-protein kinase 12; Serine/threonine-protein kinase 13; serine/threonine-protein kinase 5; Serine/threonine-protein kinase aurora-B; serine/threonine-protein kinase aurora-C; SPGF5; Stk1; STK-1; STK12; Stk13; Stk5 | |
| Rabbit | |
| Antigen Affinity Chromatography | |
| RUO | |
| 114592, 20871, 20877, 292554, 6795, 9212 | |
| Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. | |
| Liquid |
| Western Blot | |
| 1 mg/mL | |
| PBS with 15mM sodium azide; pH 7.2 | |
| O55099, O70126, O88445, Q96GD4, Q9UQB9 | |
| AURKB, AURKC | |
| Synthetic phosphopeptide derived from human AURKB/C around the phosphorylation site of Threonine 236/202. | |
| 100 μL | |
| Primary | |
| Human, Mouse, Rat | |
| Antibody | |
| IgG |
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