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Invitrogen™ Phospho-BCAR1 (Tyr410) Polyclonal Antibody

Rabbit Polyclonal Antibody
Brand: Invitrogen™ PA5110109
This item is not returnable.
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Description
Immunogen sequence: GVYAV.
The p130Cas (Cas for Crk-associated substrate) is a common cellular target of phosphorylation signal via v-Crk and v-Src oncoproteins. p130Cas has a unique structure that contains a Src homology (SH)-3 domain followed by multiple YXXP motifs and a proline-rich regionp130Cas is implicated in a variety of biological processes including cell adhesion, cell migration, growth factor stimulation, cytokine receptor engagement and bacterial infection. Physiological functions of p130Cas include cardiovascular development, actin filament assembly and Src-induced cell transformation.
Specifications
| Phospho-BCAR1 (Tyr410) | |
| Polyclonal | |
| Unconjugated | |
| BCAR1 | |
| AI385681; BCA1; Bcar1; BCAR1 scaffold protein, Cas family member; BCAR1, Cas family scaffold protein; BCAR1, Cas family scaffolding protein; breast cancer anti-estrogen resistance 1; breast cancer anti-estrogen resistance protein 1; Cas; Cas scaffolding protein family member 1; CAS1; CASS1; CRKAS; CRK-associated substrate; Crk-associated substrate p130Cas; OTTHUMP00000174941; p130 Cas; P130CAS; p130Cas (pTyr410); p130Cas (pY410); p130Cas phospho; phospho p130Cas; v-crk-associated tyrosine kinase substrate | |
| Rabbit | |
| Affinity Chromatography | |
| RUO | |
| 12927, 9564 | |
| -20°C, Avoid Freeze/Thaw Cycles | |
| Liquid |
| ELISA, Western Blot | |
| 0.94 mg/mL | |
| PBS with 50% glycerol and 0.01% thimerosal; pH 7.3 | |
| P56945, Q61140 | |
| BCAR1 | |
| A synthetic phosphorylated peptide around Y410 of human BCAR1 (NP_0553822?). | |
| 100 μL | |
| Primary | |
| Human, Mouse | |
| Antibody | |
| IgG |
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