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Invitrogen™ Phospho-Bcl-3 (Ser41) Polyclonal Antibody
Rabbit Polyclonal Antibody
Brand: Invitrogen™ PA5105525
This item is not returnable.
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Description
Antibody detects endogenous levels of BCL-3 only when phosphorylated at Ser41.
B cell Lymphoma 3 is a member of the IkB subfamily of inhibitors. This subfamily is part of the NF-kB transcription factor protein family and it is suggested that a balance in the concentration of various NF-kB family members regulates apoptosis and survival of activated T cells. Bcl-3 has been shown to have versatile functions such as cytoplasmic activation of p50 homodimers, translocation to the nucleus, and modulation of the transcriptional machinery in the nucleus. Bcl-3 activity often relies on several nuclear interacting proteins such as Tip60, Jab1, Bard1, and Pirin.
Specifications
| Phospho-Bcl-3 (Ser41) | |
| Polyclonal | |
| Unconjugated | |
| Bcl3 | |
| AI528691; B cell leukemia/lymphoma 3; B-cell CLL/lymphoma 3; B-cell leukemia/lymphoma 3; B-cell lymphoma 3 protein; B-cell lymphoma 3 protein homolog; B-cell lymphoma 3-encoded protein; BCL3; BCL-3; Bcl-3 protein; BCL4; chronic lymphatic leukemia protein; D19S37; Proto-oncogene BCL3 | |
| Rabbit | |
| Sequential Chromatography | |
| RUO | |
| 12051, 602 | |
| -20°C | |
| Liquid |
| Immunohistochemistry (Paraffin), Western Blot | |
| 1 mg/mL | |
| PBS with 50% glycerol and 0.02% sodium azide; pH 7.4 | |
| P20749, Q9Z2F6 | |
| Bcl3 | |
| A synthesized peptide derived from human BCL3(Accession P20749), corresponding to amino acid residues around phosphorylated Ser41. | |
| 100 μL | |
| Primary | |
| Human, Mouse | |
| Antibody | |
| IgG |
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