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Invitrogen™ Phospho-Beclin 1 (Ser234) Polyclonal Antibody
Rabbit Polyclonal Antibody
Brand: Invitrogen™ PA535393
This item is not returnable.
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Description
This antibody is predicted to react with bovine, canine, mouse, non-human primate, rat and sheep based on 100% sequence homology. In Western blot, additional bands may be observed when using non-immunoprecipitated lysates.
Beclin 1 plays a central role in autophagy. It acts as a core subunit of the PI3K complex that mediates formation of phosphatidylinositol 3-phosphate. Different PI3K complex forms are believed to play a role in multiple membrane trafficking pathways - PI3KC3-C1 is involved in the initation of autophagosomes and PI3KC3-C2 is involved in the maturation of autophagosomes and endocytosis. Beclin 1 also plays a role in antiviral host defense.
Specifications
| Phospho-Beclin 1 (Ser234) | |
| Polyclonal | |
| Unconjugated | |
| BECN1 | |
| 4921513J16Rik; 5430417M23Rik; APG6; Atg6; ATG6 autophagy related 6 homolog; Bcl-2-interacting protein beclin; beclin 1; beclin 1 (coiled-coil, moesin-like BCL2-interacting protein); beclin 1 (coiled-coil, myosin-like BCL2 interacting protein); beclin 1 (coiled-coil, myosin-like BCL2-interacting protein); beclin 1, autophagy related; beclin1; beclin-1; Beclin-1; beclin-1; Beclin-1-C 35 kDa; Beclin-1-C 37 kDa; becn1; Coiled-coil myosin-like BCL2-interacting protein; coiled-coil, myosin-like BCL2-interacting protein; GT197; hypothetical protein MGC73097; myosin-like BCL2 interacting protein; Protein GT197; testis secretory sperm-binding protein Li 215e; VPS30; zgc:73097 | |
| Rabbit | |
| Affinity chromatography | |
| RUO | |
| 114558, 56208, 8678 | |
| -20°C, Avoid Freeze/Thaw Cycles | |
| Liquid |
| Western Blot | |
| ~0.3 mg/mL | |
| 0.01M HEPES with 0.1mg/mL BSA, 50% glycerol, 0.15M NaCl and no preservative; pH 7.5 | |
| O88597, Q14457, Q91XJ1 | |
| BECN1 | |
| Synthetic phospho-peptide corresponding to amino acid residues surrounding Ser234 of human BECN1 conjugated to KLH. | |
| 100 μL | |
| Primary | |
| Human, Mouse, Rat | |
| Antibody | |
| IgG |
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