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Invitrogen™ Phospho-Caveolin 2 (Ser36) Polyclonal Antibody
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Product Code. 17720054
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Quantity:
100 μL
Unit Size:
100µL
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17720054 100 μL 100µL
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Product Code. 17720054 Supplier Invitrogen™ Supplier No. PA5118636

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Description

Rabbit Polyclonal Antibody

Antibody detects endogenous levels of Caveolin 2 only when phosphorylated at Ser36.

Caveolae are specialized domains of the plasma membrane that are implicated in the sequestration of a variety of lipid and protein molecules. It has been suggested that these important cellular organelles have a pivotal role in such diverse biochemical processes as lipid metabolism, growth regulation, signal transduction, and apoptosis. Caveolin interacts with and regulates heterotrimeric G-proteins. Currently, there are three members of the caveolin multigene family which are known to encode 21-24 kDa integral membrane proteins that comprise the major structural component of the caveolar membrane in vivo. Caveolin-2 protein is abundantly expressed in fibroblasts and differentiated adipocytes, smooth and skeletal muscle, and endothelial cells. The expression of caveolin-1 is similar to that of caveolin-2 while caveolin-3 expression appears to be limited to muscle tissue types.
TRUSTED_SUSTAINABILITY

Specifications

Antigen Phospho-Caveolin 2 (Ser36)
Applications Immunohistochemistry (Paraffin), Western Blot
Classification Polyclonal
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
Gene CAV2
Gene Accession No. P51636, Q2IBC5, Q9WVC3
Gene Alias AI447843; CAV; CAV2; caveolae; caveolae protein, 20-kD; caveolin 2; caveolin 2 isoform a and b; caveolin-2; MGC12294; Phospho-CAV2
Gene Symbols CAV2
Host Species Rabbit
Immunogen A synthesized peptide derived from human CAV2(Accession P51636), corresponding to amino acid residues around phosphorylated Ser36.
Purification Method sequential chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 12390, 363425, 858
Target Species Human, Mouse, Rat
Content And Storage -20°C
Product Type Antibody
Form Liquid
Isotype IgG
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