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Invitrogen™ Phospho-CDK5 (Tyr15) Polyclonal Antibody
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Product Code. 16621395
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Quantity:
100 μL
Unit Size:
100µL
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16621395 100 μL 100µL
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Product Code. 16621395 Supplier Invitrogen™ Supplier No. PA5104945

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Description

Rabbit Polyclonal Antibody

Antibody detects endogenous levels of CDK5 only when phosphorylated at Tyrosine 15.

CDK5 is a member of the Cyclin-Dependent Kinase family that is most abundant in the mammalian brain. Active form of CDK5, which has also been called neuronal cdc2-like kinase, is a heterodimer of CDK5 and a 25 kDa protein which is derived proteolytically from a 35 kDa brain and neuron-specific protein and is essential for the kinase activity of CDK5. CDK5 has emerged as a crucial regulator of neuronal migration in the developing central nervous system. CDK5 phosphorylates a diverse list of substrates, implicating it in the regulation of a range of cellular processes - from adhesion and motility, to synaptic plasticity and drug addiction.
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Specifications

Antigen Phospho-CDK5 (Tyr15)
Applications Western Blot, Immunocytochemistry
Classification Polyclonal
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
Gene CDK5
Gene Accession No. P49615, Q00535, Q03114
Gene Alias AW048668; Cdk5; CDK5 activator 1; CDK5-SV; CDKN5; Cell division protein kinase 5; CR6 protein kinase; Crk6; cyclin dependent kinase 5; cyclin-dependent kinase 5; cyclin-dependent-like kinase 5; LIS7; protein kinase CDK5 splicing; PSSALRE; Serine/threonine-protein kinase PSSALRE; tau protein kinase II catalytic subunit; TPKII catalytic subunit
Gene Symbols CDK5
Host Species Rabbit
Immunogen A synthesized peptide derived from human CDK5(Accession Q00535), corresponding to amino acid residues around phosphorylated Tyr15.
Purification Method Sequential Chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 1020, 12568, 140908
Target Species Human, Mouse, Rat, Monkey
Content And Storage -20°C
Product Type Antibody
Form Liquid
Isotype IgG
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