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Invitrogen™ Phospho-DIAPH3 (Thr1061) Polyclonal Antibody
Rabbit Polyclonal Antibody
Brand: Invitrogen™ PA5143678
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Description
The antibody detects a 135 kDa* protein corresponding to mDia2 in immunoblots of human A7r5 and mouse C2C12 cells treated with calyculin A. The antibody detects transfected mDia2 after treatment with calyculin A, but this reactivity is removed after phosphatase treatment. In addition, the antibody does not detect mDia2 (T1061A) mutant.
This gene encodes a member of the diaphanous subfamily of the formin family. Members of this family are involved in actin remodeling and regulate cell movement and adhesion. Mutations in this gene are associated with autosomal dominant auditory neuropathy 1. Multiple transcript variants encoding different isoforms have been found for this gene.
Specifications
| Phospho-DIAPH3 (Thr1061) | |
| Polyclonal | |
| Unconjugated | |
| DIAPH3 | |
| 4930417P13Rik; AN; AUNA1; DIA2; diap3; Diaph3; diaphanous homolog 3; diaphanous homolog 3 (Drosophila); diaphanous related formin 3; diaphanous-related formin; diaphanous-related formin 3; diaphanous-related formin-3; DKFZp434C0931; DKFZp686A13178; Drf3; FLJ34705; mDia2; mKIAA4117; NSDAN; p134MDia2; Protein diaphanous homolog 3 | |
| Rabbit | |
| Antigen affinity chromatography | |
| RUO | |
| 290396, 56419, 81624 | |
| -20°C, Avoid Freeze/Thaw Cycles | |
| Liquid |
| Western Blot | |
| 0.25 mg/mL | |
| PBS with 1mg/mL BSA, 50% glycerol and 0.05% sodium azide | |
| Q9NSV4, Q9Z207 | |
| DIAPH3 | |
| Phospho-mDia2 (Thr-1061) synthetic peptide (coupled to KLH) corresponding to amino acid residues surrounding Thr-1061 in mouse mDia2 (Diap3). This peptide sequence is identical in rat and has 2 amino acid differences to human mDia2. The sequence has low homology to other formins. | |
| 100 μL | |
| Primary | |
| Human, Mouse, Rat | |
| Antibody | |
| IgG |
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