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Phospho-DNA-PK (Thr2638) Polyclonal Antibody, Invitrogen™
Rabbit Polyclonal Antibody
Brand: Invitrogen PA538477
This item is not returnable.
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Description
The PRKDC gene encodes the catalytic subunit of a nuclear DNA-dependent serine/threonine protein kinase (DNA-PK). The second component is the autoimmune antigen Ku (MIM 152690), which is encoded by the G22P1 gene on chromosome 22q. On its own, the catalytic subunit of DNA-PK is inactive and relies on the G22P1 component to direct it to the DNA and trigger its kinase activity; PRKDC must be bound to DNA to express its catalytic properties.
Specifications
| Phospho-DNA-PK (Thr2638) | |
| Polyclonal | |
| Unconjugated | |
| PRKDC | |
| DNA-PKcs, DNAPK, DNPK1, HYRC, HYRC1, XRCC7, p350, DNA-PK catalytic subunit, DNA-dependent protein kinase catalytic subunit, hyper-radiosensitivity of murine scid mutation, complementing 1, p460 | |
| Rabbit | |
| Antigen affinity chromatography | |
| RUO | |
| 19090, 5591 | |
| -20°C | |
| Liquid |
| Immunocytochemistry, Immunofluorescence | |
| 1 mg/mL | |
| Dulbecco′s PBS with 150mM NaCl, 50% glycerol and 0.02% sodium azide; pH 7.4 | |
| P78527, P97313 | |
| PRKDC | |
| A synthetic phosphopeptide derived from human DNA-PK around the phosphorylation site of Thr2638 (R-A-TP-Q-Q) | |
| 100 μg | |
| Primary | |
| Human, Mouse | |
| Antibody | |
| IgG |
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