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Invitrogen™ Phospho-DUSP16 (Ser446) Polyclonal Antibody
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Product Code. 15752756
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Quantity:
100 μL
Unit Size:
100µL
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15752756 100 μL 100µL
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Product Code. 15752756 Supplier Invitrogen™ Supplier No. PA564691

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Description

Rabbit Polyclonal Antibody

Phospho-DUSP16 (Ser446) Polyclonal Antibody detects endogenous levels of DUSP16 only when phosphorylated at Ser446.

Dual-specificity phosphatases constitute a large heterogeneous subgroup of the type I cysteine-based protein-tyrosine phosphatase superfamily. DUSPs are characterized by their ability to dephosphorylate both tyrosine and serine/threonine residues. DUSP16 belongs to a class of DUSPs, designated MKPs, that dephosphorylate MAPK proteins ERK, JNK, and p38 with specificity distinct from that of individual MKP proteins. MKPs contain a highly conserved C-terminal catalytic domain and an N-terminal Cdc25-like domain. MAPK activation cascades mediate various physiologic processes, including cellular proliferation, apoptosis, differentiation, and stress responses.
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Specifications

Antigen Phospho-DUSP16 (Ser446)
Applications Western Blot
Classification Polyclonal
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
Gene DUSP16
Gene Accession No. Q9BY84
Gene Alias 3830417M17Rik; AW558566; D6Ertd213e; dual specificity phosphatase 16; dual specificity protein phosphatase 16; Dusp16; KIAA1700; MAP kinase phosphatase 7; MAP kinase phosphatase-7; map kinase phosphatase-M; MAPK phosphatase-7; MGC129701; MGC129702; mitogen-activated protein kinase phosphatase 7; Mkp7; MKP-7; Mkpm
Gene Symbols DUSP16
Host Species Rabbit
Immunogen A synthesized peptide derived from human MKP-7 (Phospho-Ser446).
Purification Method Antigen affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 70686, 80824
Target Species Human, Mouse
Content And Storage -20°C
Product Type Antibody
Form Liquid
Isotype IgG
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