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Invitrogen™ Phospho-EIF2S1 (Tyr150) Polyclonal Antibody

Rabbit Polyclonal Antibody
Brand: Invitrogen™ PA5105460
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Description
Antibody detects endogenous levels of eIF2 alpha only when phosphorylated at Tyr150.
EIF2a (Eukaryotic translation initiation factor 2A) is a heterotrimer composed of three subunits (alpha, beta, and gamma). This translation initiation factor drives binding of initiator methionyl-tRNA to the 40S ribosome in an AUG-dependent manner to form the 43S pre-initiation complex. The polypeptide can be phosphorylated by related protein kinases activated in response to stress. Phosphorylated EIF2A inhibits EIF2B activity and prevents guanine nucleotide exchange.
Specifications
| Phospho-EIF2S1 (Tyr150) | |
| Polyclonal | |
| Unconjugated | |
| EIF2S1 | |
| 0910001O23Rik; 2410026C18Rik; 35kDa; EIF2; EIF-2; eIF2 alpha; eIF2 alpha subunit; EIF2A; eIF-2A; eIF2alpha; EIF-2alpha; eIF-2-alpha; EIF2S1; eif2s1b; Eukaryotic translation initiation factor 2 subunit 1; eukaryotic translation initiation factor 2 subunit 1b; eukaryotic translation initiation factor 2 subunit alpha; eukaryotic translation initiation factor 2, subunit 1 alpha; eukaryotic translation initiation factor 2, subunit 1 alpha b; eukaryotic translation initiation factor 2, subunit 1 alpha, 35kDa; eukaryotic translation initiation factor 2A; fb19d01; translation initiation factor subunit; wu:fb19d01 | |
| Rabbit | |
| Sequential chromatography | |
| RUO | |
| 13665, 1965, 54318 | |
| -20°C | |
| Liquid |
| Immunohistochemistry (Paraffin), Western Blot | |
| 1 mg/mL | |
| PBS with 50% glycerol and 0.02% sodium azide; pH 7.4 | |
| P05198, P68101, Q6ZWX6 | |
| EIF2S1 | |
| A synthesized peptide derived from human EIF2S1(Accession P05198), corresponding to amino acid residues around phosphorylated Tyr150. | |
| 100 μL | |
| Primary | |
| Human, Mouse, Rat | |
| Antibody | |
| IgG |
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