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Invitrogen™ Phospho-ETV6 (Ser257) Polyclonal Antibody
Rabbit Polyclonal Antibody
Brand: Invitrogen™ PA5118721
This item is not returnable.
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Description
Antibody detects endogenous levels of ETV6 / Tel only when phosphorylated at Ser257.
This gene encodes an ETS family transcription factor. The product of this gene contains two functional domains: a N-terminal pointed (PNT) domain that is involved in the protein-protein interactions with itself and other proteins, and a C-terminal DNA-binding domain. Gene knockout studies in mice suggest that it is required for hematopoiesis and Maintenance of the developing vascular network. This gene is known to be involved in a large number of chromosomal rearrangements associated with leukemia and congenital fibrosarcoma.
Specifications
| Phospho-ETV6 (Ser257) | |
| Polyclonal | |
| Unconjugated | |
| Etv6 | |
| AW123102; AW557856; CGI-108; CSL4; Csl4p; ETS translocation variant 6; ETS variant 6; ets variant gene 6 (TEL oncogene); ETS-related protein Tel1; Etv6; hCsl4p; p13; RP11-452K12.9; SKI4; Ski4p; Tel; TEL/ABL; Tel1; TEL1 oncogene; THC5; Transcription factor ETV6 | |
| Rabbit | |
| Sequential Chromatography | |
| RUO | |
| 14011, 2120, 312777 | |
| -20°C | |
| Liquid |
| Immunohistochemistry (Paraffin), Western Blot | |
| 1 mg/mL | |
| PBS with 50% glycerol and 0.02% sodium azide; pH 7.4 | |
| P41212, P97360 | |
| Etv6 | |
| A synthesized peptide derived from human ETV6(Accession P41212), corresponding to amino acid residues around phosphorylated Ser257. | |
| 100 μL | |
| Primary | |
| Human, Mouse, Rat | |
| Antibody | |
| IgG |
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