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  6. 16661975

Invitrogen™ Phospho-FGFR4 (Tyr642) Polyclonal Antibody
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Rabbit Polyclonal Antibody

Brand:  Invitrogen™ PA5105531

Product Code. 16661975

  • € 500.00 / 100µL

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Description

Description

Antibody detects endogenous levels of FGFR4 only when phosphorylated at Tyr642.

FGFR4 is a member of the FGFR family of receptor tyrosine kinases. This family is known to regulate a host of cellular functions including angiogenesis, mitogenesis, osteogenesis, myogenesis, carcinogenesis, cellular differentiation, and tissue repair after injury. The FGFR family has also been implicated in a number of diseases including cancer, rheumatoid arthritis, and diabetic retinopathy. FGFR4 is required for normal down-regulation of the expression of CYP7A1, the rate-limiting enzyme in bile acid synthesis, in response to FGF19. FGFR4 plays a role in postnatal lung development and may be involved in the development of skeletal muscle cell lineages.
TRUSTED_SUSTAINABILITY
Specifications

Specifications

Phospho-FGFR4 (Tyr642)
Polyclonal
Unconjugated
Fgfr4
CD334; CTLA-2-beta protein; FGF Receptor; FGF Receptor 4; FGFR; Fgfr4; FGFR-4; Fibroblast growth factor receptor 4; fibroblast growth factor receptor 4 16 minus form; hydroxyaryl-protein kinase; JTK2; MGC20292; Mpk-11; protein-tyrosine kinase; protein-tyrosine kinase receptor MPK-11; TKF; tyrosine kinase related to fibroblast growth factor receptor; tyrosylprotein kinase
Rabbit
Sequential chromatography
RUO
14186, 2264, 25114
-20°C
Liquid
Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry
1 mg/mL
PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
P22455, Q03142, Q498D6
Fgfr4
A synthesized peptide derived from human FGFR4(Accession P22455), corresponding to amino acid residues around phosphorylated Tyr642.
100 μL
Primary
Human, Mouse, Rat
Antibody
IgG
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