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Invitrogen™ Phospho-GABBR2 (Ser783) Polyclonal Antibody

Description
This antibody is predicted to react with bovine, canine, chicken, human, mouse and non-human primate based on 100% sequence homology. In Western blot, PA1-4705 detects the ~102 kDa GABAB R2 protein phosphorylated at Ser783.
The multi-pass membrane protein, GABBR2, belongs to the G-protein coupled receptor 3 family and GABA-B receptor subfamily. The GABA-B receptors inhibit neuronal activity through G protein-coupled second-messenger systems, which regulate the release of neurotransmitters, and the activity of ion channels and adenylyl cyclase. This receptor subunit forms an active heterodimeric complex with GABA-B receptor subunit 1, neither of which is effective on its own. Allelic variants of this gene have been associated with nicotine dependence.
Specifications
Specifications
| Antigen | Phospho-GABBR2 (Ser783) |
| Applications | Immunohistochemistry, Western Blot, Immunocytochemistry |
| Classification | Polyclonal |
| Concentration | 0.25 mg/mL |
| Conjugate | Unconjugated |
| Formulation | 0.01M HEPES with 100μg/mL BSA, 50% glycerol, 0.15M NaCl and no preservative; pH 7.5 |
| Gene | GABBR2 |
| Gene Accession No. | O88871, Q80T41 |
| Gene Alias | FLJ36928; G protein-coupled receptor 51; GABA BR; GABA-B R2 receptor; GABA-B receptor 2; GABA-B receptor, R2 subunit; GABABR2; GABA-BR2; GABA-B-R2; Gabbr2; gamma-aminobutyric acid; gamma-aminobutyric acid (GABA) B receptor 2; gamma-aminobutyric acid (GABA) B receptor, 2; gamma-aminobutyric acid B receptor 2; gamma-aminobutyric acid type B receptor subunit 2; gamma-aminobutyric acid type B receptor, subunit 2; gb2; Gm425; Gpr51; GPRC3B; G-protein coupled receptor 51; HG20; HRIHFB2099; MGC119386; MGC119388; MGC119389; ortholog of human G protein-coupled receptor 51 GPR51; RP23-337N2.1 |
| Gene Symbols | GABBR2 |
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