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Invitrogen™ Phospho-gamma Catenin (Tyr550) Polyclonal Antibody
Rabbit Polyclonal Antibody
Brand: Invitrogen™ PA5143668
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Description
This antibody was cross-adsorbed to both phospho-tyrosine coupled to agarose and to dephosphorylated gamma-Catenin (Tyr-550) peptide before affinity purification using phospho-gamma-Catenin (Tyr-550) peptide (without carrier). The antibody detects an 84kDa* protein corresponding to the molecular mass of gamma-Catenin on SDS-PAGE immunoblots of A431 and Hct116 src transformed cells treated with pervanadate (1 mM for 30 min), but not in control cells.
JUP is a major cytoplasmic protein which is the only known constituent common to sub membranous plaques of both desmosomes and intermediate junctions. This protein forms distinct complexes with cadherins and desmosomal cadherins and is a member of the catenin family since it contains a distinct repeating amino acid motif called the armadillo repeat.
Specifications
| Phospho-gamma Catenin (Tyr550) | |
| Polyclonal | |
| Unconjugated | |
| JUP | |
| ARVD12; catenin (cadherin-associated protein), gamma 80kDa; Catenin gamma; cb80; cell-adhesion protein plakoglobin; Ctnng; D930025P04Rik; danPG; Desmoplakin III; desmoplakin-3; desmosomal protein; DP3; DPIII; fb11b06; gama-catenin; gamma-catenin; gamma-catenin (plakoglobin); junction plakoglobin; junction plakoglobin a; Jup; jup protein; jupa; OTTHUMP00000164735; PDGB; PG; PKGB; plakoglobin; wu:fb11b06 | |
| Rabbit | |
| Antigen affinity chromatography | |
| RUO | |
| 16480, 3728, 81679 | |
| -20°C, Avoid Freeze/Thaw Cycles | |
| Liquid |
| Western Blot, Immunocytochemistry | |
| 0.1 mg/mL | |
| PBS with 1mg/mL BSA, 50% glycerol and 0.05% sodium azide | |
| P14923, Q02257, Q6P0K8 | |
| JUP | |
| Phospho-gamma-Catenin (Tyr-550) synthetic peptide (coupled to KLH) corresponding to amino acid residues around tyrosine 550 of human gamma-Catenin. This peptide sequence is highly conserved in rat and mouse gamma-Catenin. | |
| 100 μL | |
| Primary | |
| Human, Mouse, Rat | |
| Antibody | |
| IgG |
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