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Invitrogen™ Phospho-gamma-H2AX (Ser139) Recombinant Rabbit Monoclonal Antibody (BLR053F)
Rabbit Recombinant Monoclonal Antibody
€ 156.00 - € 477.00
Specifications
| Antigen | Phospho-gamma-H2AX (Ser139) |
|---|---|
| Clone | BLR053F |
| Concentration | 100 μg/mL |
| Content And Storage | 4°C |
| Applications | Flow Cytometry, Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot, Immunocytochemistry |
| Product Code | Brand | Quantity | Price | Quantity & Availability | |||||
|---|---|---|---|---|---|---|---|---|---|
| Product Code | Brand | Quantity | Price | Quantity & Availability | |||||
|
17755669
|
Invitrogen™
MA544299 |
100 μL |
€ 477.00
100µL |
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|
17765669
|
Invitrogen™
MA544300 |
10 μL |
€ 156.00
10µL |
Please sign in to purchase this item. Need a web account? Register with us today! | |||||
Description
Epitope retrieval with citrate buffer pH6.0 is recommended for FFPE cell sections.
H2AX is a variant of the H2A protein family and is a component of the histone octomer in nucleosomes. H2AX is phosphorylated by kinases such as ataxia telangiectasia mutated (ATM) and ATM-Rad3-related (ATR) in the PI3K pathway. Gamma-H2AX is the first step in recruiting and localizing DNA repair proteins. DSBs can be induced by mechanisms such as ionizing radiation or cytotoxic agents and subsequently, gamma-H2AX foci quickly form. These foci represent the DSBs in a 1:1 manner and can be used as a biomarker for damage. The visualization of gamma-H2AX by can allow the assessment of DNA damage, related DNA damage proteins and DNA repair. Gamma-H2AX has applications in the detection of genomic damage caused by cytotoxic chemical agents and environmental and physical damage.Specifications
| Phospho-gamma-H2AX (Ser139) | |
| 100 μg/mL | |
| Flow Cytometry, Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot, Immunocytochemistry | |
| Unconjugated | |
| Rabbit | |
| RUO | |
| BBS with 0.1% BSA and 0.09% sodium azide; pH 8.2 | |
| P16104 | |
| 3014 | |
| Peptide surrounding phosphorylated serine 140 of human histone H2AX. | |
| Antibody |
| BLR053F | |
| 4°C | |
| Recombinant Monoclonal | |
| Liquid | |
| IgG | |
| Human | |
| H2AX | |
| gamma H2A X; gamma H2A.X; gamma-H2A.X; gh2ax | |
| H2AX | |
| Primary | |
| purified |
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