missing translation for 'onlineSavingsMsg'
Learn More
  1. Home
  2. Products
  3. Antibodies
  4. Primary Antibodies
  5. All Primary Antibodies
  6. 17760154

Invitrogen™ Phospho-GRK1/GRK2 (Tyr13) Polyclonal Antibody
GREENER_CHOICE

Rabbit Polyclonal Antibody

Brand:  Invitrogen™ PA5118740

Product Code. 17760154

  • € 476.00 / 100µL

Please to purchase this item. Need a web account? Register with us today!

This item is not returnable. View return policy

Description

Description

Antibody detects endogenous levels of GRK1/2 only when phosphorylated at Tyr13.

The sensation of sight is the result of a cascade of events starting with the interaction of photoactivated rhodopsin with a protein called transducin. Rhodopsin kinase is a G-protein-coupled Ser/Thr kinase, also known as GRK1, which is a key element in the regulation of this cascade. Following phosphorylation by GRK1, arrestin is recruited to phospho-rhodopsin quenching its phototransductive activity by preventing further interaction with transducin. By breaking the cycle of phototransduction, GRK1 plays an important role in the restoration of the system for subsequent visual events.
TRUSTED_SUSTAINABILITY
Specifications

Specifications

Phospho-GRK1/GRK2 (Tyr13)
Polyclonal
Unconjugated
GRK2
ADRBK1; Adrbk-1; adrenergic beta receptor kinase 1; adrenergic receptor kinase, beta 1; adrenergic, beta, receptor kinase 1; BARK; BARK1; Bark-1; beta ARK; beta-adrenergic receptor kinase 1; beta-adrenergic receptor kinase 1 beta ARK1; beta-AR kinase-1; betaARK1; BETA-ARK1; beta-ARK-1; G protein-coupled receptor kinase 1; G protein-coupled receptor kinase 2; G protein-coupled receptpr kinase 1; GPRK1; G-protein coupled receptor kinase 2; G-protein receptor kinase 1; G-protein-coupled receptor kinase 2; grk 2; GRK1; Grk2; GRK-2; rhodopsin kinase; Rhodopsin kinase GRK1; Rhok; Rk
Rabbit
Sequential chromatography
RUO
110355, 156, 24013, 25238, 6011, 81760
-20°C
Liquid
Immunohistochemistry (Paraffin), Western Blot
1 mg/mL
PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
P25098, P26817, Q15835, Q63651, Q99MK8, Q9WVL4
GRK1, GRK2
A synthesized peptide derived from human GRK2(Accession P25098), corresponding to amino acid residues around phosphorylated Tyr13.
100 μL
Primary
Human, Mouse, Rat
Antibody
IgG
Product Suggestions

Product Suggestions

Videos
SDS
Documents

Documents

Certificates
Promotions

Promotions

Product Content Correction

Your input is important to us. Please complete this form to provide feedback related to the content on this product.

Product Title

By clicking Submit, you acknowledge that you may be contacted by Fisher Scientific in regards to the feedback you have provided in this form. We will not share your information for any other purposes. All contact information provided shall also be maintained in accordance with our Privacy Policy.

Thank You! Your feedback has been submitted. Fisher Scientific is always working to improve our content for you. We appreciate your feedback.