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Phospho-Kir1.1 (Ser25, Ser44) Polyclonal Antibody, Invitrogen™
Rabbit Polyclonal Antibody
Brand: Invitrogen PA538708
This item is not returnable.
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Description
Potassium channels are present in most mammalian cells, where they participate in a wide range of physiologic responses. The protein encoded by this gene is an integral membrane protein and inward-rectifier type potassium channel. It is activated by internal ATP and probably plays an important role in potassium homeostasis. The encoded protein has a greater tendency to allow potassium to flow into a cell rather than out of a cell. Mutations in this gene have been associated with antenatal Bartter syndrome, which is characterized by salt wasting, hypokalemic alkalosis, hypercalciuria, and low blood pressure. Multiple transcript variants encoding different isoforms have been found for this gene.
Specifications
| Phospho-Kir1.1 (Ser25, Ser44) | |
| Polyclonal | |
| Unconjugated | |
| KCNJ1 | |
| KCNJ1, potassium inwardly-rectifying channel, subfamily J, member 1, KIR1.1, ROMK, ROMK1, ATP-regulated potassium channel ROM-K, ATP-sensitive inward rectifier potassium channel 1, OTTHUMP00000045938, inwardly rectifying K+ channel, potassium inwardly-rectifying channel J1 | |
| Rabbit | |
| Antigen affinity chromatography | |
| RUO | |
| 24521, 3758, 56379 | |
| -20°C | |
| Liquid |
| Peptide ELISA, Immunofluorescence, Immunohistochemistry (Paraffin) | |
| 1 mg/mL | |
| Dulbecco′s PBS with 150mM NaCl, 50% glycerol and 0.02% sodium azide; pH 7.4 | |
| P48048, O88335, P35560 | |
| KCNJ1 | |
| A synthetic phosphopeptide derived from human ROMK/Kir11 around the phosphorylation site of Ser44/25 (L-V-SP-K-D) | |
| 100 μg | |
| Primary | |
| Human, Mouse, Rat | |
| Antibody | |
| IgG |
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