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Phospho-Ku80 (Thr714) Polyclonal Antibody, Invitrogen™
Rabbit Polyclonal Antibody
Brand: Invitrogen PA538118
This item is not returnable.
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Description
XRCC5 encoded by this gene is the 80-kilodalton subunit of the Ku heterodimer protein which is also known as ATP-dependant DNA helicase II or DNA repair protein XRCC5. Ku is the DNA-binding component of the DNA-dependent protein kinase, and it functions together with the DNA ligase IV-XRCC4 complex in the repair of DNA double-strand break by non-homologous end joining and the completion of V(D)J recombination events. This gene functionally complements Chinese hamster xrs-6, a mutant defective in DNA double-strand break repair and in ability to undergo V(D)J recombination. A rare microsatellite polymorphism in this gene is associated with cancer in patients of varying radiosensitivity.
Specifications
| Phospho-Ku80 (Thr714) | |
| Polyclonal | |
| Unconjugated | |
| XRCC5 | |
| 86 kDa subunit of Ku antigen, ATP-dependent DNA helicase II, 80 kDa subunit, CTC box binding factor 85 kDa subunit, CTC85, CTCBF, DNA-repair protein XRCC5, G22P2, KU86, Lupus Ku autoantigen protein p86, Nuclear factor IV, TLAA, Thyroid- lupus autoantigen, XRCC5 | |
| Rabbit | |
| Antigen affinity chromatography | |
| RUO | |
| 7520 | |
| -20°C | |
| Liquid |
| Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot | |
| 1 mg/mL | |
| Dulbecco′s PBS with 150mM NaCl, 50% glycerol and 0.02% sodium azide; pH 7.4 | |
| P13010 | |
| XRCC5 | |
| A synthetic phosphopeptide derived from human Ku80 around the phosphorylation site of Thr714 (G-D-TP-A-A) | |
| 100 μg | |
| Primary | |
| Human, Non-human Primate | |
| Antibody | |
| IgG |
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