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Phospho-Lamin A (Ser392) Polyclonal Antibody, Invitrogen™

Product Code. 15575211
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Quantity:
100 μg
Unit Size:
100µg
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15575211 100 μg 100µg
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Product Code. 15575211 Supplier Invitrogen Supplier No. PA538290

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Description

Rabbit Polyclonal Antibody

Lamins are components of the nuclear lamina, a fibrous layer on the nucleoplasmic side of the inner nuclear membrane, which is thought to provide a framework for the nuclear envelope and may also interact with chromatin. Lamin A and C are present in equal amounts in the lamina of mammals. Plays an important role in nuclear assembly, chromatin organization, nuclear membrane and telomere dynamics. Required for normal development of peripheral nervous system and skeletal muscle and for muscle satellite cell proliferation. Required for osteoblastogenesis and bone formation. Also prevents fat infiltration of muscle and bone marrow, helping to maintain the volume and strength of skeletal muscle and bone.
TRUSTED_SUSTAINABILITY

Specifications

Antigen Phospho-Lamin A (Ser392)
Applications Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot
Classification Polyclonal
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation Dulbecco′s PBS with 150mM NaCl, 50% glycerol and 0.02% sodium azide; pH 7.4
Gene LMNA
Gene Accession No. P02545, P48678, P48679
Gene Alias Prelamin-A/C, Lamin-A/C, 70 kDa lamin, Renal carcinoma antigen NY-REN-32, LMNA, LMN1
Gene Symbols LMNA
Host Species Rabbit
Immunogen A synthetic phosphopeptide derived from human Lamin A/B (lamin A/C) around the phosphorylation site of Ser392 (S-P-SP-P-T)
Purification Method Antigen affinity chromatography
Quantity 100 μg
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 16905, 4000, 60374
Target Species Human, Mouse, Rat
Content And Storage -20°C
Product Type Antibody
Form Liquid
Isotype IgG
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