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  6. Invitrogen™ Phospho-LAT (Tyr200) Recombinant Rabbit Monoclonal Antibody (K01_1T41)

Invitrogen™ Phospho-LAT (Tyr200) Recombinant Rabbit Monoclonal Antibody (K01_1T41)
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Product Code. 30828427
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30828427 100 μL
30826731 50 μL
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Product Code. 30828427 Supplier Invitrogen™ Supplier No. MA563348

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Description

Rabbit Recombinant Monoclonal Antibody

Phospho-LAT (Tyr200) Recombinant Monoclonal Antibody for Western Blot

LAT (Linker for Activation of T cells) is a 36-38 kDa double-palmitoylated transmembrane adaptor protein expressed by T cells, pre-B cells, NK cells, mast cells and platelets. After immunoreceptor triggering, LAT becomes multiply tyrosine-phosphorylated by Syk-, Src-, or Tec-family kinases, providing docking sites for downstream signaling molecules. LAT is essential for TCR-dependent T cell- and FcepsilonRI-dependent mast cell activation, as well as for maturation of early thymocytes. It is also involved in NK cell signaling and platelet activation.
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Specifications

Antigen Phospho-LAT (Tyr200)
Applications Western Blot
Classification Recombinant Monoclonal
Clone K01_1T41
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation 50mM tris glycine with 150mM NaCl, 0.05% BSA, 40% glycerol and 0.01% sodium azide; pH 7.4
Gene LAT
Gene Accession No. O43561
Gene Alias 36 kDa phospho-tyrosine adapter protein; 36 kDa phospho-tyrosine adaptor protein; Lat; LAT1; linker for activation of T cells; linker for activation of T cells, transmembrane adaptor; linker for activation of T-cells; linker for activation of T-cells family member 1; linker protein; p36-38; pp36
Gene Symbols LAT
Host Species Rabbit
Immunogen A synthetic phosphopeptide corresponding to residues surrounding Tyr200 of human LAT.
Purification Method Protein A/G
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 27040
Target Species Human
Content And Storage Maintain refrigerated at 2-8°C for up to 1 month. For long term storage store at -20°C
Product Type Antibody
Form Liquid
Isotype IgG
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