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Invitrogen™ Phospho-mTOR (Ser2481) Polyclonal Antibody
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Rabbit Polyclonal Antibody

Brand:  Invitrogen™ PA577981

Product Code. 16306694

  • € 566.00 / 100µL

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Description

Description

Positive Control: 293T(Starvation 24 hr), 293T(Starvation 24 hr and 200 ng/mL EGF treatment for 30 min) Predicted Reactivity: Mouse (100%), Rat (100%) Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.

FRAP1 (mTOR) is a serine/threonine kinase that plays a critical role in cellular growth and proliferation. Perturbations in the mTOR/PI3-kinase/AKT pathway are associated with numerous forms of cancer. FRAP1 is also the target of rapamycin and its analogues, which are currently used as immunosuppressants and cancer therapeutics. Mutations affecting the gene results in Smith-Kingsmore syndrome.
TRUSTED_SUSTAINABILITY
Specifications

Specifications

Phospho-mTOR (Ser2481)
Polyclonal
Unconjugated
MTOR
2610315D21Rik; AI327068; angiopoietin-like factor CDT6; FK506 binding protein 12-rapamycin associated protein 1; FK506 binding protein 12-rapamycin associated protein 2; FK506-binding protein 12-rapamycin complex-associated protein 1; FKBP12-rapamycin complex-associated protein; FKBP12-rapamycin complex-associated protein 1; FKBP-rapamycin associated protein; FKBP-rapamycin associated protein (FRAP); FKBP-rapamycin-associated protein FRAP; flat; FRAP; FRAP1; FRAP2; Mammalian target of rapamycin; mechanistic target of rapamycin; mechanistic target of rapamycin (serine/threonine kinase); mechanistic target of rapamycin kinase; Mtor; m-TOR; mTORC1; Raft1; Rapamycin and FKBP12 target 1; rapamycin and FKBP12 target-1 protein; rapamycin associated protein FRAP2; rapamycin target protein 1; RAPT1; serine/threonine-protein kinase mTOR; SKS
Rabbit
Antigen affinity chromatography
RUO
2475
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Liquid
Western Blot
0.55 mg/mL
PBS with 1% BSA, 20% glycerol and 0.025% ProClin 300; pH 7
P42345
MTOR
Carrier-protein conjugated synthetic peptide surrounding phospho Ser2481 of human mTOR. The exact sequence is proprietary.
100 μL
Primary
Human
Antibody
IgG
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