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Invitrogen™ Phospho-MyD88 (Tyr257) Polyclonal Antibody
Rabbit Polyclonal Antibody
Brand: Invitrogen™ PA5106188
This item is not returnable.
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Description
Antibody detects endogenous levels of MyD88 only when phosphorylated at Tyr257.
Myeloid differentiation Marker 88 (MyD88) is an adaptor molecule for the Toll/IL-1R and is involved in the inflammatory response induced by IL-1, IL-18 and LPS. MyD88 recruits IRAK to IL-1 receptor complex in response to IL-1. This pathway further leads to activation of NF-kB. MyD88 has a wide tissue distribution.
Specifications
| Phospho-MyD88 (Tyr257) | |
| Polyclonal | |
| Unconjugated | |
| MYD88 | |
| mutant myeloid differentiation primary response 88; Myd88; MYD88D; myeloid differentiation primary response 88; myeloid differentiation primary response gene (88); myeloid differentiation primary response gene 88; myeloid differentiation primary response protein MyD88 | |
| Rabbit | |
| sequential chromatography | |
| RUO | |
| 17874, 301059, 4615 | |
| -20°C | |
| Liquid |
| Immunohistochemistry (Paraffin), Western Blot | |
| 1 mg/mL | |
| PBS with 50% glycerol and 0.02% sodium azide; pH 7.4 | |
| P22366, Q6Y1S1, Q99836 | |
| MYD88 | |
| A synthesized peptide derived from human MYD88(Accession Q99836), corresponding to amino acid residues around phosphorylated Tyr257. | |
| 100 μL | |
| Primary | |
| Human, Mouse, Rat | |
| Antibody | |
| IgG |
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