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Invitrogen™ Phospho-NF2 (Ser518) Polyclonal Antibody

Rabbit Polyclonal Antibody

Brand:  Invitrogen™ PA128383

Product Code. 11595843

  • € 520.00 / 50µg

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Description

Description

PA1-28383 detects NF2 from mouse, human samples.

NF2 encodes a protein, Merlin, that is similar to some members of the ERM family of proteins that are thought to link cytoskeletal components with proteins in the cell membrane. Merlin has been shown to interact with cell-surface proteins, proteins involved in cytoskeletal dynamics and proteins involved in regulating ion transport. This gene is expressed at high levels during embryonic development; in adults, significant expression is found in Schwann cells, meningeal cells, lens and nerve. Mutations in this gene are associated with neurofibromatosis type II which is characterized by nervous system and skin tumors and ocular abnormalities. Two predominant isoforms and a number of minor isoforms are produced by alternatively spliced transcripts.
TRUSTED_SUSTAINABILITY
Specifications

Specifications

Phospho-NF2 (Ser518)
Polyclonal
Unconjugated
Nf2
ACN; BANF; Merlin; MGC123124; moesin-ezrin-radixin like; moesin-ezrin-radixin-like protein; moesin-ezrin-radizin-like protein; neurofibromatosis 2; neurofibromin 2; neurofibromin 2 (bilateral acoustic neuroma); neurofibromin 2 (merlin); neurofibromin 2b (merlin); neurofibromin-2; Nf2; Nf-2; NF2a; nf2b; OTTHUMP00000199607; SCH; Schwannomerlin; schwannomin
Rabbit
Antigen affinity chromatography
RUO
18016, 4771
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Liquid
ELISA, Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry
1 mg/mL
PBS with 0.15M NaCl and 0.01% sodium azide; pH 7.2
P35240, P46662
Nf2
Human NF2 (Merlin) phospho-peptide corresponding to a region of the human protein surrounding S518 and conjugated to KLH.
50 μg
Primary
Human, Mouse
Antibody
IgG
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