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Invitrogen™ Phospho-NFkB p105 (Ser932) Polyclonal Antibody
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Product Code. 17742724
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Quantity:
100 μL
Unit Size:
100µL
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17742724 100 μL 100µL
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Product Code. 17742724 Supplier Invitrogen™ Supplier No. PA5121326

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Description

Rabbit Polyclonal Antibody

The target is usually found in the following locations: Cytoplasm, Nucleus. Immunogen sequence: ETSFR.

NF-kB is a nuclear transcription factor activated by various extra and intracellular stimuli such as cytokines, UV radiation, stress, in injury, and by bacterial and viral products. It is involved in regulation of various cellular events including cell growth, differentiation, proliferation, apoptosis and inflammation. NFKB1 (p50), a 50KDa functional sub-unit of NF-kB, is a member of Rel protein family. It is synthesized as a p105 precursor protein and consists of an N-terminal conserved RHD-region containing nuclear localization signal, DNA-binding and dimerization domains. NFKB1 (p50) forms homodimers or heterodimerizes with p65, forming the functional NF-kB factor. NFKB1 (p50) directs the nuclear translocation of NF-kB and is instrumental in its DNA-bidning. Pathological role of NF-kB has been suggested in AIDS, hematogenic cancer cell metastasis and rheumatoid arthritis.
TRUSTED_SUSTAINABILITY

Specifications

Antigen Phospho-NFkB p105 (Ser932)
Applications ELISA, Western Blot
Classification Polyclonal
Concentration 1.16 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.01% thimerosal; pH 7.3
Gene NFKB1
Gene Accession No. P19838
Gene Alias CVID12; DNA-binding factor KBF1; EBP-1; KBF1; NF kappaB1; NF KB; NFkappaB; NF-kappaB; NF-kappa-B; NF-kappaB p50; NF-kappaB1; NF-kappa-B1 p84/NF-kappa-B1 p98; NF-kappabeta; NF-kB; NF-kB p105; Nfkb1; NF-KB1; NFKB-p105; NFKB-p50; nuclear factor; nuclear factor kappa b; nuclear factor kappa B subunit 1; nuclear factor kappa-B 1; nuclear factor kappa-B DNA binding subunit; nuclear factor kappaB p50; nuclear factor NF-kappa-B p105 subunit; nuclear factor NF-kappa-B p105 subunit-like protein; nuclear factor NF-kappa-B p50 subunit; nuclear factor of kappa light chain gene enhancer in B-cells 1, p105; nuclear factor of kappa light polypeptide enhancer in B-cells 1; nuclear factor of kappa light polypeptide gene enhancer in B cells 1, p105; nuclear factor of kappa light polypeptide gene enhancer in B-cells 1; nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 (p105); nuclear factor of kappa light polypeptide gene enhancer in B-cells 1, p105; nuclear factor-kappaB p50; p105; p50; p50 subunit of NF kappaB; p50 subunit of NF-kappaB; p50/p105; RHD of nuclear factor NF-kappa-B p105 subunit
Gene Symbols NFKB1
Host Species Rabbit
Immunogen A synthetic phosphorylated peptide around S932 of human NFKB1 (NP_001158884.1).
Purification Method Affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 4790
Target Species Human
Content And Storage -20°C, Avoid Freeze/Thaw Cycles
Product Type Antibody
Form Liquid
Isotype IgG
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