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Invitrogen™ Phospho-p130Cas (Tyr410) Polyclonal Antibody
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Product Code. 16366994
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Quantity:
100 μL
Unit Size:
100µL
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Product Code. Quantity unitSize
16366994 100 μL 100µL
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Product Code. 16366994 Supplier Invitrogen™ Supplier No. PA578294

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Description

Rabbit Polyclonal Antibody

Positive Control: HeLa Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.

The p130Cas (Cas for Crk-associated substrate) is a common cellular target of phosphorylation signal via v-Crk and v-Src oncoproteins. p130Cas has a unique structure that contains a Src homology (SH)-3 domain followed by multiple YXXP motifs and a proline-rich regionp130Cas is implicated in a variety of biological processes including cell adhesion, cell migration, growth factor stimulation, cytokine receptor engagement and bacterial infection. Physiological functions of p130Cas include cardiovascular development, actin filament assembly and Src-induced cell transformation.
TRUSTED_SUSTAINABILITY

Specifications

Antigen Phospho-p130Cas (Tyr410)
Applications Western Blot, Immunocytochemistry
Classification Polyclonal
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with 1% BSA, 20% glycerol and 0.025% ProClin 300; pH 7
Gene BCAR1
Gene Accession No. P56945
Gene Alias AI385681; BCA1; Bcar1; BCAR1 scaffold protein, Cas family member; BCAR1, Cas family scaffold protein; BCAR1, Cas family scaffolding protein; breast cancer anti-estrogen resistance 1; breast cancer anti-estrogen resistance protein 1; Cas; Cas scaffolding protein family member 1; CAS1; CASS1; CRKAS; CRK-associated substrate; Crk-associated substrate p130Cas; OTTHUMP00000174941; p130 Cas; P130CAS; p130Cas (pTyr410); p130Cas (pY410); p130Cas phospho; phospho p130Cas; v-crk-associated tyrosine kinase substrate
Gene Symbols BCAR1
Host Species Rabbit
Immunogen Carrier-protein conjugated synthetic peptide surrounding phospho Tyr410 of human p130Cas. The exact sequence is proprietary.
Purification Method Antigen affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 9564
Target Species Human
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
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