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Invitrogen™ Phospho-PKMYT1 (Ser83) Polyclonal Antibody
Rabbit Polyclonal Antibody
Brand: Invitrogen™ PA5104618
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Description
Antibody detects endogenous levels of Myt1 only when phosphorylated at Ser83.
PKMYT1 serine/threonine kinase is a member of a family of neural specific, zinc finger-containing DNA-binding proteins which binds to the promoter regions of proteolipid proteins of the central nervous system and plays a role in the developing nervous system. MYT1 of the oligodendrocyte lineage, along with a closely related CCHC zinc finger, is expressed in developing neurons in the mammalian central nervous system. The recombinant PKMYT1 fragments containing either the upstream 2 zinc fingers or the downstream 4 zinc fingers bound the same cis regulatory element in the PLP1 promoter in vitro and DNA binding required Zn2+, but not other divalent cations.
Specifications
| Phospho-PKMYT1 (Ser83) | |
| Polyclonal | |
| Unconjugated | |
| Pkmyt1 | |
| 6230424P17; AW209059; Membrane-associated tyrosine- and threonine-specific cdc2-inhibitory kinase; membrane-associated tyrosine-and threonine-specific cdc2-inhibitory kinase; Myt1; Myt1 kinase; Pkmyt1; pkmyt1.S; PPP1R126; protein kinase, membrane associated tyrosine/threonine 1; protein kinase, membrane associated tyrosine/threonine 1 S homeolog; protein phosphatase 1, regulatory subunit 126; RGD1305434; XELAEV_18047881mg | |
| Rabbit | |
| Sequential chromatography | |
| RUO | |
| 9088 | |
| -20°C | |
| Liquid |
| Immunohistochemistry (Paraffin), Western Blot | |
| 1 mg/mL | |
| PBS with 50% glycerol and 0.02% sodium azide; pH 7.4 | |
| Q99640 | |
| Pkmyt1 | |
| A synthesized peptide derived from human PKMYT1(Accession Q99640), corresponding to amino acid residues around phosphorylated Ser83. | |
| 100 μL | |
| Primary | |
| Human | |
| Antibody | |
| IgG |
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